Cdk5rap1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdk5rap1
CDK5 regulatory subunit associated protein 1
MGI:1914221

21 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Cdk5rap1^tm1.2Tomik/Cdk5rap1^tm1.2Tomik B6J.Cg-Cdk5rap1^tm1.2Tomik	abnormal cell physiology	J:220703
	abnormal enzyme/coenzyme activity	J:220703
	abnormal mitochondrial ATP synthesis coupled electron transport	J:220703
	abnormal mitochondrial crista morphology	J:220703
	abnormal mitochondrial physiology	J:220703
	abnormal mitophagy	J:220703
	abnormal oxidative phosphorylation	J:220703
	abnormal respiratory electron transport chain	J:220703
	abnormal translation	J:220703
	normal behavior/neurological phenotype	J:220703
	cardiac hypertrophy	J:220703
	decreased calcium uptake by cardiac muscle	J:220703
	decreased cardiac muscle contractility	J:220703
	decreased circulating glucose level	J:220703
	decreased oxygen consumption	J:220703
	normal homeostasis/metabolism phenotype	J:220703
	impaired exercise endurance	J:220703
	increased mitochondrial size	J:220703
	increased response of heart to induced stress	J:220703
	increased skeletal muscle fiber mitochondrial DNA content	J:220703
	oxidative stress	J:220703

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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