Pole4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pole4
polymerase (DNA-directed), epsilon 4 (p12 subunit)
MGI:1914229

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Pole4^{tm1(KOMP)Vlcg}/Pole4^{tm1(KOMP)Vlcg} Trp53^tm1Brd/Trp53⁺ involves: C57BL/6J * C57BL/6NTac	decreased leukocyte cell number	J:261973
	decreased lymphocyte cell number	J:261973
	decreased tumor latency	J:261973
	impaired coordination	J:261973
	increased granulocyte number	J:261973
	increased monocyte cell number	J:261973
	increased T cell derived lymphoma incidence	J:261973
	prenatal lethality, incomplete penetrance	J:261973
Pole4^{tm1(KOMP)Vlcg}/Pole4^{tm1(KOMP)Vlcg} Trp53^tm1Brd/Trp53^tm1Brd involves: C57BL/6J * C57BL/6NTac	normal growth/size/body region phenotype	J:261973
	normal immune system phenotype	J:261973
	impaired coordination	J:261973
	prenatal lethality, incomplete penetrance	J:261973

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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