Fancl Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fancl
Fanconi anemia, complementation group L
MGI:1914280

37 phenotypes from 3 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fancl^gcd/Fancl^gcd B6.Cg-Fancl^gcd/Ceb	embryonic lethality during organogenesis, complete penetrance	J:80424
Fancl^gcd/Fancl^gcd involves: C57BL/6 * FVB	decreased embryo weight	J:80424
Fancl^gcd/Fancl^gcd involves: C57BL/6J * CBA/J	abnormal endometrial gland morphology	J:13553
	abnormal estrous cycle	J:13553
	abnormal female reproductive system morphology	J:21254
	abnormal seminiferous tubule morphology	J:21254
	absent estrous cycle	J:13553
	decreased corpora lutea number	J:21254
	decreased primordial germ cell number	J:21254, J:80424
	decreased primordial germ cell proliferation	J:80424
	decreased superovulation rate	J:13553
	failure of superovulation	J:13553
	female infertility	J:13553, J:21254
	impaired ovarian folliculogenesis	J:13553, J:21254
	increased circulating follicle stimulating hormone level	J:13553
	male infertility	J:21254
	oligozoospermia	J:21254
	ovary cyst	J:21254
	small epididymis	J:21254
	small ovary	J:13553, J:21254
	small testis	J:21254
	small uterine cervix	J:21254
	small uterus	J:13553, J:21254
	thin myometrium	J:13553, J:21254
Fancl^gcd/Fancl^tm1Ceb involves: 129/Sv * C57BL/6	prenatal lethality, complete penetrance	J:80424
Fancl^gcd/Fancl^tm1Ceb involves: 129/Sv * C57BL/6 * FVB/N	abnormal Sertoli cell morphology	J:80424
	absent germ cells	J:80424
	female infertility	J:80424
	male infertility	J:80424
	small testis	J:80424
Fancl^gcd/Fancl^tm1Ceb involves: 129S7/SvEvBrd * C57BL/6J * CBA	prenatal lethality, complete penetrance	J:80424
Fancl^{tm1b(EUCOMM)Hmgu}/Fancl^{tm1b(EUCOMM)Hmgu} C57BL/6N-Fancl^{tm1b(EUCOMM)Hmgu}/Nju	abnormal bone structure	J:211773
	abnormal coat/hair pigmentation	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased lean body mass	J:211773
	increased basophil cell number	J:211773
	increased eosinophil cell number	J:211773
	increased total body fat amount	J:211773
Fancl^tm1Ceb/Fancl^tm1Ceb 129/Sv-Fancl^tm1Ceb	prenatal lethality, complete penetrance	J:80424
Fancl^tm1Ceb/Fancl^tm1Ceb either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * FVB/N)	abnormal seminiferous tubule morphology	J:80424
	decreased male germ cell number	J:80424
	female infertility	J:80424
	impaired ovarian folliculogenesis	J:80424
	male infertility	J:80424
	small ovary	J:80424
	small testis	J:80424
	small uterus	J:80424
Fancl^tm1Ceb/Fancl^tm1Ceb involves: 129/Sv * C57BL/6	prenatal lethality, complete penetrance	J:80424

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