Dynlrb1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dynlrb1
dynein light chain roadblock-type 1
MGI:1914318

13 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dynlrb1^{tm1a(EUCOMM)Wtsi}/Dynlrb1⁺ C57BL/6N-Dynlrb1^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal bone structure	J:211773
Dynlrb1^{tm1a(EUCOMM)Wtsi}/Dynlrb1⁺ involves: C57BL/6N	abnormal dorsal root ganglion morphology	J:292124
Dynlrb1^{tm1a(EUCOMM)Wtsi}/Dynlrb1⁺ Tg(Thy1-YFP)16Jrs/0 involves: C57BL/6J * C57BL/6N	abnormal axon extension	J:292124
Dynlrb1^{tm1a(EUCOMM)Wtsi}/Dynlrb1^{tm1a(EUCOMM)Wtsi} C57BL/6N-Dynlrb1^{tm1a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Dynlrb1^{tm1a(EUCOMM)Wtsi}/Dynlrb1^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	embryonic lethality, complete penetrance	J:292124
Dynlrb1^{tm1c(EUCOMM)Wtsi}/Dynlrb1^{tm1c(EUCOMM)Wtsi} involves: 129S4/SvJaeSor * C57BL/6N	abnormal axonal transport	J:292124
Dynlrb1^{tm1c(EUCOMM)Wtsi}/Dynlrb1^{tm1c(EUCOMM)Wtsi} Runx3^{tm6(EGFP/cre)Yg}/Runx3⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N	abnormal gait	J:292124
	abnormal motor coordination/balance	J:292124
	abnormal proprioceptive neuron morphology	J:292124
	decreased locomotor activity	J:292124
	impaired balance	J:292124
	limb grasping	J:292124
	normal nervous system phenotype	J:292124

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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