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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
MGI:1914342
64 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gatmem1Btlr/Gatmem1Btlr
C57BL/6J-Gatmem1Btlr 		abnormal enterocyte proliferation J:252049
decreased colon length J:252049
decreased creatine level J:252049
normal immune system phenotype J:252049
increased enterocyte apoptosis J:252049
increased physiological sensitivity to xenobiotic J:252049
increased susceptibility to induced colitis J:252049
Gatmem1Btlr/Gatmm1Btlr
C57BL/6J-Gatmem1Btlr/Gatmm1Btlr 		decreased colon length J:252049
diarrhea J:252049
increased susceptibility to induced colitis J:252049
increased susceptibility to weight loss J:252049
Gatmm1Btlr/Gatm+
C57BL/6J-Gatmm1Btlr 		increased susceptibility to induced colitis J:252049
increased susceptibility to xenobiotic induced morbidity/mortality J:252049
Gatmm1Btlr/Gatmm1Btlr
C57BL/6J-Gatmm1Btlr 		abnormal duodenum crypts of Lieberkuhn morphology J:252049
decreased colon length J:252049
decreased creatine level J:252049
diarrhea J:252049
increased enterocyte apoptosis J:252049
increased susceptibility to induced colitis J:252049
increased susceptibility to weight loss J:252049
increased susceptibility to xenobiotic induced morbidity/mortality J:252049
Gatmtm1.1Isb/Gatmtm1.1Isb
B6.129-Gatmtm1.1Isb 		abnormal eating behavior J:191142
abnormal gluconeogenesis J:191142
abnormal glucose homeostasis J:191142
abnormal spermatogenesis J:191142
abnormal testis morphology J:191142
abnormal urine amino acid level J:191142
decreased body length J:191142
decreased body mass index J:191142
decreased body weight J:191142
decreased circulating cholesterol level J:191142
decreased circulating glucose level J:191142
decreased circulating insulin level J:191142
decreased circulating leptin level J:191142
decreased circulating triglyceride level J:191142
decreased liver triglyceride level J:191142
decreased locomotor activity J:191142
decreased subcutaneous adipose tissue amount J:191142
decreased susceptibility to diet-induced hepatic steatosis J:191142
decreased susceptibility to diet-induced obesity J:191142
decreased total body fat amount J:191142
decreased urine creatine level J:191142
decreased urine creatinine level J:191142
decreased white adipose tissue amount J:191142
female infertility J:191142
normal growth/size/body region phenotype J:191142
normal homeostasis/metabolism phenotype J:191142
hypotonia J:191142
improved glucose tolerance J:191142
increased adipocyte glucose uptake J:191142
increased muscle cell glucose uptake J:191142
male infertility J:191142
scoliosis J:191142
Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi
C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg 		abnormal QT variability J:211773
abnormal sinus arrhythmia J:211773
cardiovascular system phenotype J:211773
decreased circulating alkaline phosphatase level J:211773
decreased circulating cholesterol level J:211773
decreased exploration in new environment J:211773
decreased food intake J:211773
decreased grip strength J:211773
decreased heart rate J:211773
decreased locomotor activity J:211773
decreased prepulse inhibition J:211773
decreased red blood cell distribution width J:211773
decreased respiratory quotient J:211773
female infertility J:211773
increased circulating amylase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating potassium level J:211773
increased heart rate variability J:211773
increased mean corpuscular hemoglobin J:211773
male infertility J:211773
prolonged QRS complex duration J:211773
prolonged QT interval J:211773
prolonged RR interval J:211773
prolonged ST segment J:211773
thrombocytopenia J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory