Fgf22 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgf22
fibroblast growth factor 22
MGI:1914362

11 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgf22^{tm1b(EUCOMM)Hmgu}/Fgf22^{tm1b(EUCOMM)Hmgu} C57BL/6N-Fgf22^{tm1b(EUCOMM)Hmgu}/H	abnormal gait	J:211773
	increased circulating amylase level	J:211773
Fgf22^tm1Dgen/Fgf22^tm1Dgen B6.Cg-Fgf22^tm1Dgen	decreased susceptibility to pharmacologically induced seizures	J:161954
Fgf22^tm1Dgen/Fgf22^tm1Dgen Not Specified	abnormal synaptic vesicle clustering	J:161954
	abnormal synaptic vesicle morphology	J:161954
	abnormal synaptic vesicle number	J:161954
	decreased miniature excitatory postsynaptic current frequency	J:161954
	enhanced paired-pulse facilitation	J:161954
	increased synaptic depression	J:161954
Fgf22^tm1Rpgr/Fgf22^tm1Rpgr involves: 129P2/OlaHsd * C57BL/6	decreased incidence of tumors by chemical induction	J:187809
	normal integument phenotype	J:187809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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