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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Taok1
TAO kinase 1
MGI:1914490
26 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Taok1em1(IMPC)Tcp/Taok1+
C57BL/6NCrl-Taok1em1(IMPC)Tcp/Tcp 		abnormal lens morphology J:211773
abnormal retina blood vessel morphology J:211773
abnormal retina vasculature morphology J:211773
abnormal skin morphology J:211773
cataract J:211773
Taok1em1(IMPC)Tcp/Taok1em1(IMPC)Tcp
C57BL/6NCrl-Taok1em1(IMPC)Tcp/Tcp 		preweaning lethality, complete penetrance J:211773
Taok1em1Bcgen/Taok1+
C57BL/6N-Taok1em1Bcgen 		abnormal cerebral cortex morphology J:341142
abnormal neuron physiology J:341142
abnormal postsynaptic density morphology J:341142
abnormal Raphe nucleus morphology J:341142
abnormal vocalization J:341142
normal behavior/neurological phenotype J:341142
decreased body weight J:341142
decreased grip strength J:341142
decreased social investigation J:341142
decreased social novelty preference J:341142
decreased vocalization J:341142
hyperactivity J:341142
hypotonia J:341142
increased brain size J:341142
increased brain weight J:341142
increased grooming behavior J:341142
increased stereotypic behavior J:341142
megacephaly J:341142
normal taste/olfaction phenotype J:341142
Taok1em1Bcgen/Taok1em1Bcgen
C57BL/6N-Taok1em1Bcgen 		lethality, complete penetrance J:341142
Taok1em1Cya/Taok1em1Cya
C57BL/6J-Taok1em1Cya 		decreased social investigation J:341142
increased grooming behavior J:341142
increased stereotypic behavior J:341142
Taok1em1Cya/Taok1em1Cya
Tg(Slc17a8-icre)1Edw/0
involves: C57BL/6J * FVB/N 		decreased social investigation J:341142
increased grooming behavior J:341142
increased stereotypic behavior J:341142
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/02/2024
MGI 6.13 		The Jackson Laboratory