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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Peli1
pellino 1
MGI:1914495
30 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Peli1tm1.1Arte/Peli1tm1.1Arte
involves: C57BL/6N 		abnormal cytokine secretion J:191578
abnormal peripheral lymph node morphology J:191578
abnormal salivary gland morphology J:191578
decreased interferon-alpha secretion J:191578
decreased interferon-beta secretion J:191578
decreased interleukin-6 secretion J:191578
decreased interleukin-10 secretion J:191578
decreased interleukin-12 secretion J:191578
decreased tumor necrosis factor secretion J:191578
enlarged lymph nodes J:191578
normal immune system phenotype J:191578
lethality, incomplete penetrance J:191578
lymphoid hyperplasia J:191578
Peli1tm1b(EUCOMM)Wtsi/Peli1tm1b(EUCOMM)Wtsi
C57BL/6N-Peli1tm1b(EUCOMM)Wtsi/Ucd 		abnormal spleen morphology J:211773
decreased body length J:211773
decreased brain weight J:211773
enlarged heart J:211773
enlarged spleen J:211773
improved glucose tolerance J:211773
increased lean body mass J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Peli1tm1Tigm/Peli1tm1Tigm
involves: 129/Sv * C57BL/6 		decreased B cell proliferation J:152781
decreased circulating interferon-beta level J:152781
decreased circulating interleukin-6 level J:152781
decreased circulating interleukin-12b level J:152781
decreased circulating tumor necrosis factor level J:152781
decreased interleukin-12 secretion J:152781
decreased susceptibility to endotoxin shock J:152781
decreased susceptibility to xenobiotic induced morbidity/mortality J:152781
increased B cell apoptosis J:152781
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory