Slc39a10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc39a10
solute carrier family 39 (zinc transporter), member 10
MGI:1914515

31 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^tm1(cre)Reth/Cd79a⁺ Slc39a10^tm1.1Tfk/Slc39a10^tm1.1Tfk involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J	decreased B cell number	J:213935
	decreased IgA level	J:213935
	decreased IgE level	J:213935
	decreased IgG1 level	J:213935
	decreased IgG2b level	J:213935
	decreased IgG2c level	J:213935
	decreased IgG3 level	J:213935
	decreased IgM level	J:213935
	decreased immunoglobulin level	J:213935
	decreased pro-B cell number	J:213935
	spleen atrophy	J:213935
Slc39a10^em1(IMPC)J/Slc39a10⁺ C57BL/6NJ-Slc39a10^em1(IMPC)J/Mmjax	abnormal coat/ hair morphology	J:211773
	abnormal coat/hair pigmentation	J:211773
	abnormal vocalization	J:211773
	increased grip strength	J:211773
Slc39a10^em1(IMPC)J/Slc39a10^em1(IMPC)J C57BL/6NJ-Slc39a10^em1(IMPC)J/Mmjax	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Slc39a10^tm1.1Tfk/Slc39a10^tm1.1Tfk Tg(Foxn1-cre)8Ghr/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2	increased thymocyte apoptosis	J:254216
	thymus hypoplasia	J:254216
Slc39a10^tm1.1Tfk/Slc39a10^tm1.1Tfk Tg(KRT14-cre)1Amc/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal epidermal layer morphology	J:254216
	abnormal epidermis stratum granulosum morphology	J:254216
	abnormal epidermis stratum spinosum morphology	J:254216
	abnormal skin development	J:254216
	decreased epidermal stem cell number	J:254216
	decreased hair follicle number	J:254216
	impaired skin barrier function	J:254216
	postnatal lethality, complete penetrance	J:254216
	reddish skin	J:254216
	sparse hair	J:254216
	thin epidermis	J:254216
	thin epidermis stratum granulosum	J:254216

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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