Socs4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Socs4
suppressor of cytokine signaling 4
MGI:1914546

20 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Socs4^m1Nch/Socs4^m1Nch C3H/He-Socs4^m1Nch	normal embryo phenotype	J:241977
	normal growth/size/body region phenotype	J:241977
	normal immune system phenotype	J:241977
	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:241977
	normal reproductive system phenotype	J:241977
Socs4^m1Nch/Socs4^m1Nch C6.C3Fe-Socs4^m1Nch	embryo phenotype	J:241977
	growth/size/body region phenotype	J:241977
	immune system phenotype	J:241977
	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:241977
	reproductive system phenotype	J:241977
Socs4^m1Nch/Socs4^m1Nch C.C3Fe-Socs4^m1Nch	abnormal chemokine secretion	J:241977
	abnormal T cell activation	J:241977
	decreased T cell number	J:241977
	normal embryo phenotype	J:241977
	normal growth/size/body region phenotype	J:241977
	normal immune system phenotype	J:241977
	increased interferon-gamma secretion	J:241977
	increased interleukin-1 secretion	J:241977
	increased interleukin-4 secretion	J:241977
	increased interleukin-5 secretion	J:241977
	increased interleukin-6 secretion	J:241977
	increased interleukin-12b secretion	J:241977
	increased interleukin-13 secretion	J:241977
	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:241977
	increased T cell number	J:241977
	normal reproductive system phenotype	J:241977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24