Socs4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Socs4
suppressor of cytokine signaling 4
MGI:1914546

20 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Socs4^m1Nch/Socs4^m1Nch C3H/He-Socs4^m1Nch	normal embryo phenotype	J:241977
	normal growth/size/body region phenotype	J:241977
	normal immune system phenotype	J:241977
	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:241977
	normal reproductive system phenotype	J:241977
Socs4^m1Nch/Socs4^m1Nch C6.C3Fe-Socs4^m1Nch	embryo phenotype	J:241977
	growth/size/body region phenotype	J:241977
	immune system phenotype	J:241977
	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:241977
	reproductive system phenotype	J:241977
Socs4^m1Nch/Socs4^m1Nch C.C3Fe-Socs4^m1Nch	abnormal chemokine secretion	J:241977
	abnormal T cell activation	J:241977
	decreased T cell number	J:241977
	normal embryo phenotype	J:241977
	normal growth/size/body region phenotype	J:241977
	normal immune system phenotype	J:241977
	increased interferon-gamma secretion	J:241977
	increased interleukin-1 secretion	J:241977
	increased interleukin-4 secretion	J:241977
	increased interleukin-5 secretion	J:241977
	increased interleukin-6 secretion	J:241977
	increased interleukin-12b secretion	J:241977
	increased interleukin-13 secretion	J:241977
	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:241977
	increased T cell number	J:241977
	normal reproductive system phenotype	J:241977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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