Gpx7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gpx7
glutathione peroxidase 7
MGI:1914555

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gpx7^{tm1.1(KOMP)Vlcg}/Gpx7^{tm1.1(KOMP)Vlcg} C57BL/6N-Gpx7^{tm1.1(KOMP)Vlcg}/Ucd	abnormal eye morphology	J:211773
	absent optic nerve	J:211773
	increased erythrocyte cell number	J:211773
	increased hematocrit	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Gpx7^tm1Whle/Gpx7^tm1Whle involves: 129P2/OlaHsd * C57BL/6	abnormal humoral immune response	J:193993
	enlarged heart	J:193993
	enlarged spleen	J:193993
	glomerulonephritis	J:193993
	hepatic steatosis	J:193993
	increased anti-nuclear antigen antibody level	J:193993
	increased cellular sensitivity to hydrogen peroxide	J:193993
	increased cellular sensitivity to oxidative stress	J:193993
	increased fibroblast apoptosis	J:193993
	increased leukemia incidence	J:193993
	increased lung adenocarcinoma incidence	J:193993
	increased lymphoma incidence	J:193993
	increased mammary adenocarcinoma incidence	J:193993
	increased salivary gland tumor incidence	J:193993
	increased sarcoma incidence	J:193993
	increased tumor incidence	J:193993
	oxidative stress	J:193993
	premature death	J:193993
	stomach mucosa hyperplasia	J:193993
	vascular inflammation	J:193993

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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