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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Daam1
dishevelled associated activator of morphogenesis 1
MGI:1914596
30 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Daam1Gt(RRT390)Byg/Daam1Gt(RRT390)Byg
involves: 129P2/OlaHsd * C57BL/6J 		abnormal cell adhesion J:167714
abnormal fetal cardiomyocyte morphology J:167714
abnormal fibroblast physiology J:167714
abnormal heart left ventricle morphology J:167714
abnormal heart ventricle morphology J:167714
abnormal muscle physiology J:167714
abnormal sarcomere morphology J:167714
normal cardiovascular system phenotype J:167714
cyanosis J:167714
decreased fetal size J:167714
decreased survivor rate J:167714
double outlet right ventricle J:167714
fetal cardiomyocyte disarray J:167714
impaired wound healing J:167714
lethality throughout fetal growth and development, incomplete penetrance J:167714
neonatal lethality, incomplete penetrance J:167714
pericardial effusion J:167714
ventricular septal defect J:167714
Daam1Gt(RRT390)Byg/Daam1Gt(RRT390)Byg
Nkx2-5tm1(cre)Rjs/Nkx2-5+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J 		normal cardiovascular system phenotype J:167714
decreased body size J:167714
decreased embryo size J:167714
normal mortality/aging J:167714
Daam1tm1.1Tpy/Daam1tm1.1Tpy
Nkx2-5tm1(cre)Rjs/Nkx2-5+
involves: 129S1/Sv * 129S7/SvEvBrd 		abnormal diastolic filling velocity J:228507
abnormal heart left ventricle morphology J:228507
abnormal heart right ventricle morphology J:228507
abnormal myocardial trabeculae morphology J:228507
abnormal pulmonary pressure J:228507
normal cardiovascular system phenotype J:228507
decreased right ventricle systolic pressure J:228507
thin ventricle myocardium compact layer J:228507
Daam1tm1b(EUCOMM)Hmgu/Daam1+
C57BL/6N-Daam1tm1b(EUCOMM)Hmgu/H 		increased blood urea nitrogen level J:211773
increased circulating amylase level J:211773
Daam1tm1b(EUCOMM)Hmgu/Daam1tm1b(EUCOMM)Hmgu
C57BL/6N-Daam1tm1b(EUCOMM)Hmgu/H 		preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory