Abcg8 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abcg8
ATP binding cassette subfamily G member 8
MGI:1914720

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Abcg5^tm1.1Hobb/Abcg5^tm1.1Hobb Abcg8^tm1.1Hobb/Abcg8^tm1.1Hobb Speer6-ps1^{Tg(Alb-cre)21Mgn}/? involves: C57BL/6 * DBA * SJL	abnormal cellular cholesterol metabolism	J:215443
	abnormal feces composition	J:215443
	abnormal intestinal cholesterol absorption	J:215443
	abnormal phytosterol level	J:215443
	decreased cholesterol efflux	J:215443
	decreased circulating cholesterol level	J:215443
	decreased phytosterol level	J:215443
	increased cholesterol level	J:215443
	increased circulating phytosterol level	J:215443
Abcg5^tm1.1Hobb/Abcg5^tm1.1Hobb Abcg8^tm1.1Hobb/Abcg8^tm1.1Hobb Tg(CAG-cre/Esr1)5Amc/? involves: C57BL/6 CBA * SJL	abnormal cellular cholesterol metabolism	J:215443
	abnormal feces composition	J:215443
	abnormal phytosterol level	J:215443
	decreased cholesterol efflux	J:215443
	decreased cholesterol level	J:215443
	decreased circulating cholesterol level	J:215443
	decreased phytosterol level	J:215443
	increased circulating phytosterol level	J:215443
	increased intestinal phytosterol absorption	J:215443
	increased phytosterol level	J:215443
Abcg5^tm1.1Hobb/Abcg5^tm1.1Hobb Abcg8^tm1.1Hobb/Abcg8^tm1.1Hobb Tg(Vil1-cre)997Gum/? involves: C57BL/6 * SJL	abnormal cellular cholesterol metabolism	J:215443
	abnormal feces composition	J:215443
	decreased cholesterol efflux	J:215443
	increased circulating phytosterol level	J:215443
	increased intestinal phytosterol absorption	J:215443
	increased phytosterol level	J:215443

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24