Rab39b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rab39b
RAB39B, member RAS oncogene family
MGI:1915040

29 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rab39b^em1(IMPC)Tcp/Y C57BL/6NCrl-Rab39b^em1(IMPC)Tcp/Tcp	abnormal skin morphology	J:211773
	abnormal stomach morphology	J:211773
	decreased heart weight	J:211773
	decreased spleen weight	J:211773
	enlarged urinary bladder	J:211773
Rab39b^em1(IMPC)Tcp/Rab39b^em1(IMPC)Tcp C57BL/6NCrl-Rab39b^em1(IMPC)Tcp/Tcp	abnormal auditory brainstem response	J:211773
	abnormal freezing behavior	J:211773
	abnormal liver morphology	J:211773
	decreased fasting circulating glucose level	J:211773
	hydrometra	J:211773
	increased circulating aspartate transaminase level	J:211773
	small ovary	J:211773
	tremors	J:211773
Rab39b^em1Jfch/Y C57BL/6N-Rab39b^em1Jfch	abnormal cerebral cortex morphology	J:287752
	abnormal motor learning	J:287752
	abnormal response to social novelty	J:287752
	normal behavior/neurological phenotype	J:287752
	decreased body weight	J:287752
	normal growth/size/body region phenotype	J:287752
	increased brain size	J:287752
	increased brain weight	J:287752
	increased cerebral cortex cell number	J:287752
	normal mortality/aging	J:287752
	normal reproductive system phenotype	J:287752
Rab39b^em1Jfch/Rab39b^em1Jfch C57BL/6N-Rab39b^em1Jfch	decreased body weight	J:287752
	normal growth/size/body region phenotype	J:287752
	increased brain size	J:287752
	increased brain weight	J:287752
	normal mortality/aging	J:287752
	normal reproductive system phenotype	J:287752
Rab39b^tm1Pdad/Y B6N.Cg-Rab39b^tm1Pdad	abnormal dendritic spine morphology	J:341888
	abnormal spatial working memory	J:341888
	decreased social investigation	J:341888
	impaired cued conditioning behavior	J:341888
	increased dendritic spine density	J:341888

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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