Ccdc80 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccdc80
coiled-coil domain containing 80
MGI:1915146

23 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccdc80^tm1.1Ftk/Ccdc80^tm1.1Ftk involves: 129P2/OlaHsd * BALB/cJ * C57BL/6N	normal digestive/alimentary phenotype	J:216704
	increased hepatocellular carcinoma incidence	J:216704
	normal mortality/aging	J:216704
Ccdc80^tm1Ftk/Ccdc80^tm1Ftk involves: 129P2/OlaHsd * C57BL/6N	no abnormal phenotype detected	J:216704
Ccdc80^tm1Ftrm/Ccdc80^tm1Ftrm C57BL/6-Ccdc80^tm1Ftrm	abnormal food intake	J:189183
	decreased circulating insulin level	J:189183
	decreased oxygen consumption	J:189183
	enhanced lipolysis	J:189183
	normal homeostasis/metabolism phenotype	J:189183
	impaired glucose tolerance	J:189183
	increased circulating free fatty acids level	J:189183
	increased circulating glucose level	J:189183
	increased circulating leptin level	J:189183
	increased food intake	J:189183
	increased insulin secretion	J:189183
	increased susceptibility to weight gain	J:189183
	increased total body fat amount	J:189183
	pancreatic islet hyperplasia	J:189183
Ccdc80^tm1Ppal/Ccdc80⁺ Not Specified	increased fibroblast proliferation	J:217742
Ccdc80^tm1Ppal/Ccdc80^tm1Ppal Not Specified	decreased fibroblast apoptosis	J:217742
	increased fibroblast proliferation	J:217742
	increased metastatic potential	J:217742
	increased ovarian carcinoma incidence	J:217742
	increased thyroid adenoma incidence	J:217742

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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