Plpp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plpp3
phospholipid phosphatase 3
MGI:1915166

39 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plpp3^{tm1b(EUCOMM)Hmgu}/Plpp3⁺ C57BL/6N-Plpp3^{tm1b(EUCOMM)Hmgu}/Cnrm	decreased mean corpuscular hemoglobin	J:211773
	increased circulating creatinine level	J:211773
Plpp3^{tm1b(EUCOMM)Hmgu}/Plpp3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Plpp3^{tm1b(EUCOMM)Hmgu}/Cnrm	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Plpp3^tm1Stw/Plpp3^tm1Stw either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal allantois morphology	J:84753
	abnormal embryo turning	J:84753
	abnormal extraembryonic tissue morphology	J:84753
	abnormal phospholipid level	J:84753
	abnormal vasculogenesis	J:84753
	abnormal vitelline vascular remodeling	J:84753
	abnormal vitelline vasculature morphology	J:84753
	absent vitelline blood vessels	J:84753
	disorganized yolk sac vascular plexus	J:84753
	embryonic growth retardation	J:84753
	embryonic lethality during organogenesis, complete penetrance	J:84753
	failure of chorioallantoic fusion	J:84753
	hemorrhage	J:84753
	pale yolk sac	J:84753
Plpp3^tm1Stw/Plpp3^tm1Stw involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal anterior visceral endoderm morphology	J:84753
	abnormal embryonic tissue morphology	J:84753
	abnormal gastrulation	J:84753
	abnormal neural tube morphology	J:84753
	abnormal notochord morphology	J:84753
	abnormal primitive node morphology	J:84753
	abnormal primitive streak morphology	J:84753
	abnormal rostral-caudal axis patterning	J:84753
	embryonic-extraembryonic boundary constriction	J:84753
	increased axial mesoderm size	J:84753
	increased somite number	J:84753
	rostral body truncation	J:84753
	rostral-caudal axis duplication	J:84753
	short rostral-caudal axis	J:84753
Plpp3^tm2Stw/Plpp3^tm2Stw involves: 129S1/Sv * C57BL/6J	abnormal allantois morphology	J:142493
	abnormal gastrulation	J:142493
	abnormal vitelline vascular remodeling	J:142493
	embryonic growth retardation	J:142493
	failure of chorioallantoic fusion	J:142493
	open neural tube	J:142493
	prenatal lethality	J:142493
Plpp3^tm3.1Stw/Plpp3^tm3.1Stw involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal allantois morphology	J:125025
	abnormal embryo turning	J:125025
	abnormal neural fold morphology	J:125025
	abnormal vitelline vasculature morphology	J:125025
	embryonic growth retardation	J:125025
	enlarged allantois	J:125025
	failure of chorioallantoic fusion	J:125025
	hemorrhage	J:125025
	kinked neural tube	J:125025
	prenatal lethality, complete penetrance	J:125025
Plpp3^tm3Stw/Plpp3^tm3Stw involves: 129S1/Sv * C57BL/6J	no abnormal phenotype detected	J:125025

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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