Kmt5a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kmt5a
lysine methyltransferase 5A
MGI:1915206

9 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kmt5a^{Gt(RRB075)Byg}/Kmt5a^{Gt(RRB075)Byg} involves: 129P2/OlaHsd	embryonic lethality, complete penetrance	J:136565
Kmt5a^tm1.1Dare/Kmt5a^tm1.1Dare involves: 129S1/Sv * C57BL/6 * SJL	no abnormal phenotype detected	J:147765
Kmt5a^tm1.1Dare/Kmt5a^tm1.2Dare Tg(CAG-cre/Esr1)5Amc/0 involves: 129S1/Sv C57BL/6 * CBA * SJL	abnormal cell cycle checkpoint function	J:147765
	abnormal cell physiology	J:147765
	abnormal DNA repair	J:147765
	decreased DNA replication	J:147765
	increased apoptosis	J:147765
Kmt5a^tm1.2Dare/Kmt5a^tm1.2Dare involves: 129S1/Sv * C57BL/6 * CBA * SJL	embryonic lethality before implantation, complete penetrance	J:147765
	failure of zygotic cell division	J:147765

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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