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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sdhaf4
succinate dehydrogenase complex assembly factor 4
MGI:1915252
15 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Sdhaf4em1Bcgen/Sdhaf4em1Bcgen
B6.Cg-Sdhaf4em1Bcgen A1cfTg(Myh6-cre/Esr1*)1Jmk 		enlarged heart J:345348
premature death J:345348
Sdhaf4em1Bcgen/Sdhaf4em1Bcgen
Tg(Ckmm-cre)5Khn/0
B6.Cg-Sdhaf4em1Bcgen Tg(Ckmm-cre)5Khn 		abnormal cardiac muscle contractility J:345348
abnormal mitochondrial physiology J:345348
abnormal myocardial fiber mitochondrial morphology J:345348
abnormal myocardial fiber morphology J:345348
abnormal tricarboxylic acid cycle J:345348
cardiac fibrosis J:345348
decreased body weight J:345348
decreased heart left ventricle muscle contractility J:345348
decreased myocardial fiber mitochondrial DNA content J:345348
dilated cardiomyopathy J:345348
dilated heart ventricle J:345348
enlarged heart J:345348
increased heart weight J:345348
premature death J:345348
thick myocardium J:345348
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory