Cert1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cert1
ceramide transporter 1
MGI:1915268

49 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cert1^{Gt(RRF047)Byg}/Cert1^{Gt(RRF047)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal cardiac outflow tract development	J:146172
	abnormal cardiovascular system physiology	J:146172
	abnormal cell physiology	J:146172
	abnormal endoplasmic reticulum morphology	J:146172
	abnormal heart morphology	J:146172
	abnormal lipid homeostasis	J:146172
	abnormal mitochondrial morphology	J:146172
	abnormal mitochondrial physiology	J:146172
	normal cellular phenotype	J:146172
	decreased cell proliferation	J:146172
	decreased embryo size	J:146172
	decreased heart ventricle muscle contractility	J:146172
	embryonic lethality during organogenesis, complete penetrance	J:146172
	increased cardiac jelly amount	J:146172
	increased heart ventricle size	J:146172
	thin ventricular wall	J:146172
Cert1^tm1.1Jsau/Cert1^tm1.1Jsau involves: 129S/SvEv * BALB/cJ * C57BL/6	abnormal muscle development	J:177789
	normal homeostasis/metabolism phenotype	J:177789
	normal reproductive system phenotype	J:177789
Cert1^{tm1a(KOMP)Wtsi}/Cert1⁺ C57BL/6N-Cert1^{tm1a(KOMP)Wtsi}/Wtsi	decreased mean corpuscular hemoglobin	J:211773
Cert1^{tm1a(KOMP)Wtsi}/Cert1^{tm1a(KOMP)Wtsi} C57BL/6N-Cert1^{tm1a(KOMP)Wtsi}/Wtsi	abnormal cervical rib	J:239583
	abnormal forebrain morphology	J:239583
	abnormal nasal cavity morphology	J:239583
	abnormal optic cup morphology	J:239583
	abnormal pectinate muscle morphology	J:239583
	abnormal placenta morphology	J:261316
	abnormal placental labyrinth vasculature morphology	J:261316
	abnormal semicircular canal morphology	J:239583
	abnormal trophoblast layer morphology	J:261316
	abnormal umbilical vein topology	J:239583
	abnormal vertebral arch morphology	J:239583
	abnormal vertebral artery topology	J:239583
	absent tibia	J:239583
	aphakia	J:239583
	decreased cervical vertebrae number	J:239583
	double outlet right ventricle	J:239583
	fetal growth retardation	J:239583
	fusion of vertebral arches	J:239583
	fusion of vertebral bodies	J:239583
	heterochrony	J:239583
	muscular ventricular septal defect	J:239583
	perimembraneous ventricular septal defect	J:239583
	persistent right dorsal aorta	J:239583
	persistent trigeminal artery	J:239583
	persistent truncus arteriosus	J:239583
	placenta hemorrhage	J:261316
	placenta necrosis	J:261316
	preweaning lethality, incomplete penetrance	J:211773, J:261316
	small placenta	J:261316

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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