Pak1ip1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pak1ip1
PAK1 interacting protein 1
MGI:1915333

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pak1ip1^em1(IMPC)Tcp/Pak1ip1^em1(IMPC)Tcp C57BL/6NCrl-Pak1ip1^em1(IMPC)Tcp/Tcp	embryonic lethality prior to organogenesis	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Pak1ip1^mray/Pak1ip1^mray involves: C57BL/6J * FVB/NJ	abnormal brain ventricle morphology	J:204457
	abnormal craniofacial development	J:204457
	abnormal masseter muscle morphology	J:204457
	abnormal maxilla morphology	J:204457
	abnormal midface morphology	J:204457
	cleft secondary palate	J:204457
	decreased cell proliferation	J:204457
	decreased fetal size	J:204457
	decreased forebrain size	J:204457
	decreased hindbrain size	J:204457
	facial cleft	J:204457
	fetal growth retardation	J:204457
	increased midbrain size	J:204457
	lethality throughout fetal growth and development, complete penetrance	J:204457
	palatal shelves fail to meet at midline	J:204457
	skin edema	J:204457
	small nasal septum	J:204457

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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