Pak1ip1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pak1ip1
PAK1 interacting protein 1
MGI:1915333

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pak1ip1^em1(IMPC)Tcp/Pak1ip1^em1(IMPC)Tcp C57BL/6NCrl-Pak1ip1^em1(IMPC)Tcp/Tcp	embryonic lethality prior to organogenesis	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Pak1ip1^mray/Pak1ip1^mray involves: C57BL/6J * FVB/NJ	abnormal brain ventricle morphology	J:204457
	abnormal craniofacial development	J:204457
	abnormal masseter muscle morphology	J:204457
	abnormal maxilla morphology	J:204457
	abnormal midface morphology	J:204457
	cleft secondary palate	J:204457
	decreased cell proliferation	J:204457
	decreased fetal size	J:204457
	decreased forebrain size	J:204457
	decreased hindbrain size	J:204457
	facial cleft	J:204457
	fetal growth retardation	J:204457
	increased midbrain size	J:204457
	lethality throughout fetal growth and development, complete penetrance	J:204457
	palatal shelves fail to meet at midline	J:204457
	skin edema	J:204457
	small nasal septum	J:204457

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24