Arl13b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arl13b
ADP-ribosylation factor-like 13B
MGI:1915396

33 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arl13b^hnn/Arl13b^hnn involves: C3HeB/FeJ * C57BL/6J	abnormal left-right axis patterning	J:98216
	absent floor plate	J:98216
	embryonic lethality during organogenesis, complete penetrance	J:98216
Arl13b^hnn/Arl13b^hnn involves: C57BL/6J	spina bifida	J:173637
Arl13b^hnn/Arl13b^tm1Tc Pax3^tm1(cre)Joe/Pax3⁺ involves: 129S6/SvEvTac * C57BL/6J	decreased body size	J:173637
	perinatal lethality, incomplete penetrance	J:173637
	postnatal lethality, complete penetrance	J:173637
	respiratory distress	J:173637
Arl13b^tm1.1Tc/Arl13b^tm1.1Tc Pde6g^{tm1(cre/ERT2)Eye}/Pde6g⁺ involves: 129S6/SvEvTac * C57BL/6J	abnormal electroretinogram waveform feature	J:272501
	abnormal photoreceptor connecting cilium morphology	J:272501
	abnormal photoreceptor outer segment morphology	J:272501
	retina photoreceptor degeneration	J:272501
Arl13b^tm1.1Tc/Arl13b^tm1.1Tc Tg(Six3-cre)69Frty/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2	abnormal electroretinogram waveform feature	J:272501
	abnormal ocular fundus morphology	J:272501
	abnormal photoreceptor connecting cilium morphology	J:272501
	abnormal photoreceptor outer segment disc membrane morphology	J:272501
	abnormal photoreceptor outer segment morphology	J:272501
	abnormal retina development	J:272501
	decreased total retina thickness	J:272501
	retina photoreceptor degeneration	J:272501
	short photoreceptor inner segment	J:272501
	short photoreceptor outer segment	J:272501
Arl13b^{tm1c(EUCOMM)Wtsi}/Arl13b^{tm1c(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	no abnormal phenotype detected	J:240795
Arl13b^{tm1c(EUCOMM)Wtsi}/Arl13b^{tm1c(EUCOMM)Wtsi} Tg(Cdh16-cre)91Igr/0 involves: C57BL/6J * C57BL/6N * ICR	absent kidney epithelial cell primary cilium	J:240795
	dilated kidney collecting duct	J:240795
	enlarged kidney	J:240795
	increased blood urea nitrogen level	J:240795
	increased kidney cell proliferation	J:240795
	increased kidney weight	J:240795
	kidney cortex cyst	J:240795
	kidney cyst	J:240795
	kidney failure	J:240795
	kidney medulla cyst	J:240795
	polycystic kidney	J:240795
	premature death	J:240795
	renal fibrosis	J:240795
	renal interstitial fibrosis	J:240795

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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