About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rpa1
replication protein A1
MGI:1915525
17 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Rpa1tm1b(KOMP)Wtsi/Rpa1+
C57BL/6N-Rpa1tm1b(KOMP)Wtsi/J 		decreased circulating free fatty acids level J:211773
decreased circulating glucose level J:211773
decreased erythrocyte cell number J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
increased heart weight J:211773
increased mean corpuscular volume J:211773
Rpa1tm1b(KOMP)Wtsi/Rpa1tm1b(KOMP)Wtsi
C57BL/6N-Rpa1tm1b(KOMP)Wtsi/J 		embryonic lethality prior to organogenesis J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Rpa1tm1Wed/Rpa1+
involves: 129/Sv * C57BL/6J * SJL 		abnormal definitive hematopoiesis J:99303
chromosome breakage J:99303
increased lymphocyte cell number J:99303
increased lymphoma incidence J:99303
premature death J:99303
Rpa1tm1Wed/Rpa1tm1Wed
involves: 129/Sv * C57BL/6J * SJL 		decreased cell proliferation J:99303
embryonic lethality before implantation, complete penetrance J:99303
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory