Mto1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mto1
mitochondrial tRNA translation optimization 1
MGI:1915541

28 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Mto1^{Gt(G019A03)Wrst}/Mto1^{Gt(G019A03)Wrst} involves: 129S2/SvPas * C57BL/6J	abnormal behavioral response to anesthetic	J:223246
	abnormal mitochondrial inner membrane morphology	J:223246
	abnormal mitochondrial physiology	J:223246
	abnormal motor coordination/balance	J:223246
	abnormal response to novel object	J:223246
	atrioventricular block	J:223246
	cardiac muscle necrosis	J:223246
	cardiomyopathy	J:223246
	decreased anxiety-related response	J:223246
	decreased body weight	J:223246
	decreased heart rate	J:223246
	decreased myocardial fiber mitochondrial DNA content	J:223246
	decreased QRS amplitude	J:223246
	decreased startle reflex	J:223246
	dilated heart	J:223246
	dilated sarcoplasmic reticulum	J:223246
	impaired coordination	J:223246
	increased grip strength	J:223246
	increased heart weight	J:223246
	increased locomotor activity	J:223246
	increased physiological sensitivity to xenobiotic	J:223246
	increased susceptibility to xenobiotic induced morbidity/mortality	J:223246
	irregular heartbeat	J:223246
	myocardial fiber degeneration	J:223246
	prolonged QRS complex duration	J:223246
	prolonged QT interval	J:223246
	sinoatrial block	J:223246
	ventricular premature beat	J:223246

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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