Chn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chn1
chimerin 1
MGI:1915674

45 phenotypes from 11 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chn1^em1(IMPC)J/Chn1⁺ C57BL/6NJ-Chn1^em1(IMPC)J/J	decreased circulating glucose level	J:211773
	decreased circulating iron level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating sodium level	J:211773
Chn1^em1(IMPC)J/Chn1^em1(IMPC)J C57BL/6NJ-Chn1^em1(IMPC)J/J	preweaning lethality, incomplete penetrance	J:211773
Chn1^Gt714Lex/Chn1^Gt714Lex involves: 129S5/SvEvBrd	abnormal gait	J:128698
	abnormal locomotor behavior	J:128698
	abnormal motor neuron innervation pattern	J:128698
	abnormal muscle electrophysiology	J:128698
	abnormal spinal cord interneuron morphology	J:128698
	abnormal spinal nerve morphology	J:128698
	normal nervous system phenotype	J:128698
Chn1^mfy/Chn1^mfy involves: C57BL/6	abnormal cerebral cortex morphology	J:125703
	abnormal corticospinal tract morphology	J:125703
	abnormal gait	J:125703
	abnormal nervous system electrophysiology	J:125703
	abnormal spinal cord dorsal column morphology	J:125703
	decreased body weight	J:125703
Chn1^{tm1.1(KOMP)Vlcg}/Chn1^{tm1.1(KOMP)Vlcg} B6N(Cg)-Chn1^{tm1.1(KOMP)Vlcg}/J	abnormal sleep behavior	J:211773
	decreased circulating chloride level	J:211773
	decreased circulating free fatty acids level	J:211773
	decreased circulating glucose level	J:211773
	decreased exploration in new environment	J:211773
	decreased total body fat amount	J:211773
	hyperactivity	J:211773
	impaired righting response	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating sodium level	J:211773
	increased hematocrit	J:211773
	increased hemoglobin content	J:211773
	increased lean body mass	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773
Chn1^tm1.1Abet/Chn1^tm1.1Abet involves: 129P2/OlaHsd * FVB/N	abnormal axon extension	J:128724
	abnormal central pattern generator function	J:128724
	abnormal gait	J:128724
	abnormal innervation	J:128724
	decreased body size	J:128724
	enlarged brain ventricles	J:128724
	tonic seizures	J:128724
	unidirectional circling	J:128724
Chn1^tm1.1Ece/Chn1⁺ Tg(Hlxb9-GFP)1Tmj/0 involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J	abnormal abducens nerve morphology	J:243785
	abnormal eye morphology	J:243785
	abnormal innervation	J:243785
Chn1^tm1.1Ece/Chn1^tm1.1Ece Tg(Hlxb9-GFP)1Tmj/0 involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J	abnormal abducens nerve morphology	J:243785
	abnormal axon fasciculation	J:243785
	abnormal eye morphology	J:243785
	abnormal innervation	J:243785
Chn1^tm1.1Ece/Chn1^tm1.1Ece Tg(Isl1-EGFP)1Slp/0 involves: 129S1/Sv 129S6/SvEvTac * BALB/c * C57BL/6J	abnormal innervation	J:243785
	decreased motor neuron number	J:243785
Chn1^tm1.1Ito/Chn1^tm1.1Ito involves: C57BL/6NSlc	abnormal corticospinal tract morphology	J:125703
	abnormal gait	J:125703, J:209606
	abnormal nervous system electrophysiology	J:125703
	abnormal spinal cord dorsal column morphology	J:125703
	abnormal spinal cord morphology	J:125703, J:209606
Chn1^tm1.1Schei/Chn1^tm1.1Schei B6.129S6(Cg)-Chn1^tm1.1Schei	no abnormal phenotype detected	J:101977
Chn1^tm1.2Ece/Chn1^tm1.2Ece Tg(Hlxb9-GFP)1Tmj/0 involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J	abnormal abducens nerve morphology	J:243785
	abnormal innervation	J:243785
	normal vision/eye phenotype	J:243785
Chn1^tm1Ito/Chn1^tm1.1Ito Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas * C57BL/6NSlc	normal behavior/neurological phenotype	J:209606
Chn1^tm1Ito/Chn1^tm1.1Ito Tg(Slc17a6-icre)1Oki/0 involves: C57BL/6 * C57BL/6NSlc	abnormal gait	J:209606
	abnormal nerve fiber response	J:209606
	abnormal spinal cord morphology	J:209606
Chn1^tm2Abet/Chn1^tm2Abet involves: 129P2/OlaHsd * FVB/N	abnormal axon extension	J:128724
	abnormal gait	J:128724
	decreased body size	J:128724
	enlarged brain ventricles	J:128724
	tonic seizures	J:128724

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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