Rraga Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rraga
Ras-related GTP binding A
MGI:1915691

23 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺ Rraga^tm2Dmsa/Rraga^tm2Dmsa involves: 129S/SvEv * 129S4/SvJae * C57BL/6	abnormal intestine apoptosis	J:213516
	decreased B cell number	J:213516
	enlarged spleen	J:213516
	increased apoptosis	J:213516
	increased lymphoma incidence	J:213516
	increased monocyte cell number	J:213516
	myeloid hyperplasia	J:213516
	premature death	J:213516
	weight loss	J:213516
Rraga^tm1.1Dmsa/Rraga^tm1.1Dmsa involves: 129 * C57BL/6 * C57BL/6J	abnormal autophagy	J:194401
	abnormal circulating amino acid level	J:194401
	abnormal gluconeogenesis	J:194401
	abnormal glycogen homeostasis	J:194401
	decreased birth weight	J:194401
	normal homeostasis/metabolism phenotype	J:194401
	hypoglycemia	J:194401
	increased susceptibility to induced morbidity/mortality	J:194401
	neonatal lethality, complete penetrance	J:194401
Rraga^tm1Dmsa/Rraga^tm1Dmsa involves: 129 * C57BL/6	decreased embryo size	J:213516
	embryonic lethality during organogenesis, complete penetrance	J:213516
	open neural tube	J:213516
Rraga^tm2.1Dmsa/Rraga^tm2.1Dmsa involves: 129S4/SvJae * C57BL/6	decreased embryo size	J:213516
	embryonic lethality during organogenesis, complete penetrance	J:213516
	open neural tube	J:213516
Rraga^tm2Dmsa/Rraga^tm2Dmsa Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S4/SvJae * C57BL/6 * DBA	decreased circulating glucose level	J:213516
	increased insulin sensitivity	J:213516

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24