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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Eml1
echinoderm microtubule associated protein like 1
MGI:1915769
61 phenotypes from 5 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Eml1em1(IMPC)Wtsi/Eml1em1(IMPC)Wtsi
C57BL/6N-Eml1em1(IMPC)Wtsi/Wtsi 		absent pinna reflex J:211773
decreased erythrocyte cell number J:211773
decreased fasting circulating glucose level J:211773
increased mean corpuscular hemoglobin J:211773
Eml1heco/?
involves: CD-1 		abnormal brain development J:211342
abnormal cortical intermediate zone morphology J:211342
abnormal mitotic spindle morphology J:211342
abnormal neuronal precursor proliferation J:211342
abnormal radial glial cell morphology J:211342
ectopic neuron J:211342
increased neuron apoptosis J:211342
Eml1heco/Eml1heco
involves: C57BL/6 * NOR 		ectopic cortical neuron J:208031
Eml1heco/Eml1heco
involves: NOR 		abnormal cortical intermediate zone morphology J:208031
abnormal cranium morphology J:208031
abnormal locomotor activation J:208031
abnormal locomotor behavior J:208031
abnormal righting response J:208031
bradykinesia J:208031
brain atrophy J:208031
decreased body size J:208031
decreased body weight J:208031
decreased locomotor activity J:208031
delayed eyelid opening J:208031
delayed hair appearance J:208031
ectopic cortical neuron J:208031
enlarged brain ventricles J:208031
impaired spatial learning J:208031
increased susceptibility to pharmacologically induced seizures J:208031
myoclonus J:208031
normal nervous system phenotype J:208031
seizures J:208031
thickened cerebral cortex J:208031
Eml1m1Btlr/Eml1m1Btlr
C57BL/6J-Eml1m1Btlr 		round head J:272865
Eml1tm1.2Ics/Eml1+
C57BL/6N-Eml1tm1.2Ics 		abnormal cortical plate morphology J:294769
abnormal embryonic/fetal subventricular zone morphology J:294769
decreased anterior commissure size J:294769
premature death J:294769
Eml1tm1.2Ics/Eml1tm1.2Ics
C57BL/6N-Eml1tm1.2Ics 		abnormal brain morphology J:294769
abnormal cerebral cortex morphology J:294769
abnormal cortical intermediate zone morphology J:294769
abnormal cortical plate morphology J:294769
abnormal cortical ventricular zone morphology J:294769
abnormal dorsal subiculum morphology J:294769
abnormal embryonic/fetal subventricular zone morphology J:294769
abnormal hippocampus CA3 region morphology J:294769
abnormal hippocampus pyramidal cell layer J:294769
abnormal neuronal precursor proliferation J:294769
absent corpus callosum J:294769
decreased anterior commissure size J:294769
decreased cingulate cortex size J:294769
ectopic neuron J:294769
enlarged lateral ventricles J:294769
hydrocephaly J:294769
premature death J:294769
preweaning lethality, incomplete penetrance J:294769
small lateral ventricles J:294769
thin cerebral cortex J:294769
Eml1tvrm360/Eml1tvrm360
C57BL/6J-Eml1tvrm360/Pjn 		abnormal cone electrophysiology J:297748
abnormal Muller cell morphology J:297748
abnormal photoreceptor outer segment disc membrane morphology J:297748
abnormal retina development J:297748
abnormal retina horizontal cell morphology J:297748
abnormal retina morphology J:297748
abnormal retina neuronal layer morphology J:297748
abnormal retina progenitor cell morphology J:297748
abnormal rod electrophysiology J:297748
decreased a-wave amplitude J:297748
decreased b-wave amplitude J:297748
dilated lateral ventricle J:297748
ectopic neuron J:297748
obstructive hydrocephaly J:297748
premature death J:297748
preweaning lethality, incomplete penetrance J:297748
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory