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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zfyve21
zinc finger, FYVE domain containing 21
MGI:1915770
16 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Zfyve21tm2c(EUCOMM)Wtsi/Zfyve21tm2c(EUCOMM)Wtsi
Tg(Cdh5-cre/ERT2)1Rha/0
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N 		abnormal body weight J:350543
abnormal glomerular endothelium fenestra morphology J:350543
abnormal glomerular filtration barrier function J:350543
abnormal kidney physiology J:350543
abnormal peritubular capillary morphology J:350543
abnormal renal filtration J:350543
abnormal renal glomerulus morphology J:350543
abnormal renal water homeostasis J:350543
decreased body weight J:350543
decreased circulating serum albumin level J:350543
decreased podocyte number J:350543
decreased renal glomerular filtration rate J:350543
edema J:350543
increased circulating creatinine level J:350543
increased glomerular capsule space J:350543
increased vascular permeability J:350543
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory