Tefm Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tefm
transcription elongation factor, mitochondrial
MGI:1915800

11 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tefm^tm1.1Lrsn/Tefm^tm1.1Lrsn Tg(Ckmm-cre)5Khn/0 involves: C57BL/6N * FVB	abnormal mitochondrial ATP synthesis coupled electron transport	J:276874
	abnormal mitochondrial morphology	J:276874
	abnormal myocardial fiber morphology	J:276874
	decreased body weight	J:276874
	enlarged heart	J:276874
	increased heart weight	J:276874
	increased mitochondrial DNA content	J:276874
	premature death	J:276874
Tefm^tm1.2Lrsn/Tefm^tm1.2Lrsn involves: C57BL/6N	absent heart tube	J:276874
	decreased embryo size	J:276874
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:276874

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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