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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
MGI:1915826
11 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lamtor5tm1b(EUCOMM)Hmgu/Lamtor5+
C57BL/6N-Lamtor5tm1b(EUCOMM)Hmgu/Bay 		abnormal coat appearance J:211773
abnormal skin coloration J:211773
decreased total retina thickness J:211773
Lamtor5tm1b(EUCOMM)Hmgu/Lamtor5tm1b(EUCOMM)Hmgu
C57BL/6N-Lamtor5tm1b(EUCOMM)Hmgu/Bay 		embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Lamtor5tm1Lye/Lamtor5tm1Lye
Not Specified 		decreased insulin secretion J:258406
Lamtor5tm1Lye/Lamtor5tm1Lye
Tg(Ins2-cre)25Mgn/0
involves: C57BL/6 * DBA 		abnormal pancreatic islet morphology J:258406
decreased circulating insulin level J:258406
decreased insulin secretion J:258406
normal growth/size/body region phenotype J:258406
impaired glucose tolerance J:258406
increased fasting circulating glucose level J:258406
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory