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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rtn4
reticulon 4
MGI:1915835
13 phenotypes from 9 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Rtn4em1(IMPC)Hmgu/Rtn4em1(IMPC)Hmgu
C57BL/6NCrl-Rtn4em1(IMPC)Hmgu/Ieg 		abnormal auditory brainstem response J:211773
abnormal startle reflex J:211773
decreased prepulse inhibition J:211773
decreased startle reflex J:211773
increased mean platelet volume J:211773
Rtn4Gt715Lex/Rtn4Gt715Lex
involves: 129S5/SvEvBrd * C57BL/6 		abnormal axon extension J:133355
Rtn4Gt(OST45048)Lex/Rtn4Gt(OST45048)Lex
involves: 129S5/SvEvBrd 		enhanced central nervous system regeneration J:83193
Rtn4Gt(OST45048)Lex/Rtn4Gt(OST45048)Lex
involves: 129S5/SvEvBrd * C57BL/6 		normal nervous system phenotype J:151085
Rtn4tm1Matl/Rtn4tm1Matl
involves: 129S7/SvEvBrd * C57BL/6 		abnormal nervous system physiology J:83192
Rtn4tm1Schw/Rtn4tm1Schw
involves: 129S6/SvEvTac * C57BL/6 		enhanced central nervous system regeneration J:107700
Rtn4tm2.1Matl/Rtn4tm2.1Matl
involves: 129S7/SvEvBrd * C57BL/6 		embryonic lethality J:83192
Rtn4tm2Matl/Rtn4tm2Matl
involves: 129S7/SvEvBrd * C57BL/6 		embryonic lethality, complete penetrance J:83192
normal nervous system phenotype J:83192
Rtn4tm3.1Matl/Rtn4tm3.1Matl
involves: 129S7/SvEvBrd 		no abnormal phenotype detected J:83192
Rtn4tm3.1Matl/Rtn4tm3.1Matl
involves: 129S7/SvEvBrd * C57BL/6 		abnormal central nervous system regeneration J:151085
Rtn4tm3Matl/Rtn4tm3Matl
involves: 129S7/SvEvBrd 		no abnormal phenotype detected J:83192
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/21/2024
MGI 6.24 		The Jackson Laboratory