Cthrc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cthrc1
collagen triple helix repeat containing 1
MGI:1915838

38 phenotypes from 7 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cthrc1^em1(IMPC)Mbp/Cthrc1^em1(IMPC)Mbp C57BL/6NCrl-Cthrc1^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	persistence of hyaloid vascular system	J:211773
	small kidney	J:211773
	small liver	J:211773
	small testis	J:211773
Cthrc1^tm1.1Suna/Cthrc1^tm1.1Suna Ctsk^tm1(cre)Ska/Ctsk⁺ involves: 129S6/SvEvTac * C57BL/6NCrlj * C57BL/6NTac * CBA/JNCrlj	abnormal osteoid morphology	J:201631
	decreased bone mass	J:201631
	decreased bone ossification	J:201631
	decreased bone trabecula number	J:201631
	decreased trabecular bone thickness	J:201631
	increased bone trabecular spacing	J:201631
	osteoporosis	J:201631
	normal skeleton phenotype	J:201631
Cthrc1^tm1.1Suna/Cthrc1^tm1.1Suna Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: 129S6/SvEvTac * C57BL/6NTac * CD-1	normal skeleton phenotype	J:201631
Cthrc1^tm1.2Suna/Cthrc1^tm1.2Suna involves: 129S6/SvEvTac * C57BL * C57BL/6NTac * DBA	decreased bone mass	J:201631
	decreased bone trabecula number	J:201631
	decreased trabecular bone thickness	J:201631
	osteoporosis	J:201631
Cthrc1^tm1Haak/Cthrc1^tm1Haak B6.129S-Cthrc1^tm1Haak	abnormal bone ossification	J:143940
	abnormal osteoblast morphology	J:143940
	abnormal osteoblast physiology	J:143940
	decreased bone trabecula number	J:143940
	decreased osteoblast cell number	J:143940
	decreased osteoblast proliferation	J:143940
	decreased trabecular bone mass	J:143940
	normal skeleton phenotype	J:143940
Cthrc1^tm1Hssk/Cthrc1^tm1Hssk either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)	no abnormal phenotype detected	J:140886
Cthrc1^tm1Vli/Cthrc1^tm1Vli 129S6.Cg-Cthrc1^tm1Vli	increased circulating glucose level	J:192096
	increased liver glycogen level	J:192096
	increased skeletal muscle glycogen level	J:192096
	insulin resistance	J:192096
Cthrc1^tm1Vli/Cthrc1^tm1Vli B6.Cg-Cthrc1^tm1Vli	abnormal hepatocyte morphology	J:192096
	liver hypoplasia	J:192096
	macrovesicular hepatic steatosis	J:192096
	microvesicular hepatic steatosis	J:192096
Tg(Col1a1-Cthrc1)1Haak/0 B6.Cg-Tg(Col1a1-Cthrc1)1Haak	abnormal bone ossification	J:143940
	abnormal osteoblast physiology	J:143940
	abnormal trabecular bone morphology	J:143940
	increased bone mass	J:143940
	increased bone trabecula number	J:143940
	increased osteoblast cell number	J:143940
	increased osteoblast proliferation	J:143940
	increased trabecular bone mass	J:143940
	normal skeleton phenotype	J:143940

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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