Tab2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
MGI:1915902

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Tab2^tm2.1Aki/Tab2^tm2.1Aki Tab3^tm1Aki/Tab3^tm1Aki Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal B cell physiology	J:195289
	abnormal immune serum protein physiology	J:195289
	decreased B cell proliferation	J:195289
	decreased B-1a cell number	J:195289
	decreased circulating interleukin-6 level	J:195289
	decreased IgD level	J:195289
	decreased IgE level	J:195289
	decreased IgG level	J:195289
	decreased immunoglobulin level	J:195289
	decreased mature B cell number	J:195289
	decreased plasma cell number	J:195289
	increased B cell apoptosis	J:195289
Tab2^tm2.1Aki/Tab2^tm2.1Aki Tab3^tm1Aki/Tab3^tm1Aki Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:195289
Tab2^tm2.1Aki/Tab2^tm2.1Aki Tnfrsf1a^tm1Mak/Tnfrsf1a^tm1Mak Tg(Tek-cre)12Flv/0 involves: 129P2/OlaHsd * C3H * C57BL/6	abnormal vascular development	J:191285
	embryonic lethality during organogenesis, complete penetrance	J:191285

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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