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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nexn
nexilin
MGI:1916060
18 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nexnem1Chen/Nexnem1Chen
C57BL/6J-Nexnem1Chen 		abnormal heart echocardiography feature J:301807
abnormal myocardial fiber morphology J:301807
decreased cardiac muscle contractility J:301807
dilated cardiomyopathy J:301807
increased heart left ventricle size J:301807
preweaning lethality, incomplete penetrance J:301807
Nexntm1.1Chen/Nexn+
Not Specified 		normal cardiovascular system phenotype J:301807
Nexntm1.1Chen/Nexntm1.1Chen
Not Specified 		abnormal heart echocardiography feature J:290931
abnormal ventricular thrombosis J:290931
decreased body weight J:290931
decreased cardiac muscle contractility J:290931
dilated cardiomyopathy J:290931
dilated heart left ventricle J:290931
enlarged heart J:290931
increased heart weight J:290931
postnatal lethality, complete penetrance J:290931
Nexntm1.1Zhh/Nexn+
involves: C57BL/6NTac 		dilated cardiomyopathy J:228046
Nexntm1.1Zhh/Nexntm1.1Zhh
involves: C57BL/6NTac 		abnormal heart morphology J:228046
cardiac fibrosis J:228046
decreased cardiac muscle contractility J:228046
dilated cardiomyopathy J:228046
dilated heart left ventricle J:228046
increased heart left ventricle size J:228046
increased heart weight J:228046
postnatal lethality, incomplete penetrance J:228046
Nexntm1Chen/Nexntm1Chen
Not Specified 		abnormal myocardial fiber physiology J:290931
Nexntm1Chen/Nexntm1Chen
Tg(myl7.L-cre)1118Tmhn/0
involves: MF1 		abnormal heart echocardiography feature J:290931
abnormal myocardial fiber morphology J:290931
abnormal myocardial fiber physiology J:290931
abnormal ventricular thrombosis J:290931
decreased body size J:290931
decreased body weight J:290931
dilated cardiomyopathy J:290931
increased heart weight J:290931
postnatal lethality, complete penetrance J:290931
Nexntm1Chen/Nexntm1Chen
Tg(Tnnt2-cre)5Blh/0
involves: C57BL/6 * DBA/2 		dilated cardiomyopathy J:290931
postnatal lethality, complete penetrance J:290931
Nexntm2.1Chen/Nexntm2.1Chen
Not Specified 		normal cardiovascular system phenotype J:301807
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory