Ppil1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
MGI:1916066

26 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppil1^em1(IMPC)Mbp/Ppil1⁺ C57BL/6N-Ppil1^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal skin morphology	J:211773
	decreased exploration in new environment	J:211773
	increased circulating creatinine level	J:211773
	microphthalmia	J:211773
	polycystic kidney	J:211773
	small kidney	J:211773
	small spleen	J:211773
Ppil1^em1(IMPC)Mbp/Ppil1^em1(IMPC)Mbp C57BL/6N-Ppil1^em1(IMPC)Mbp/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Ppil1^em2Jgg/Ppil1^em2Jgg C57BL/6-Ppil1^em2Jgg	embryonic lethality, complete penetrance	J:300487
Ppil1^em2Jgg/Ppil1^em3Jgg C57BL/6-Ppil1^em2Jgg Ppil1^em3Jgg	decreased embryo size	J:300487
Ppil1^em3Jgg/Ppil1^em3Jgg C57BL/6-Ppil1^em3Jgg	abnormal cerebral cortex morphology	J:300487
	decreased cerebral cortex average cell area	J:300487
	decreased forebrain volume	J:300487
	forebrain hypoplasia	J:300487
	increased neuron apoptosis	J:300487
	loss of cortex neurons	J:300487
	microcephaly	J:300487
	neonatal lethality, complete penetrance	J:300487
	thin cerebral cortex	J:300487
Ppil1^em4Jgg/Ppil1^em4Jgg C57BL/6-Ppil1^em4Jgg	increased neuron apoptosis	J:300487
	loss of cortex neurons	J:300487
	microcephaly	J:300487
	perinatal lethality, complete penetrance	J:300487
	thin cerebral cortex	J:300487
Ppil1^em5Jgg/Ppil1^em5Jgg C57BL/6-Ppil1^em5Jgg	normal mortality/aging	J:300487
	normal nervous system phenotype	J:300487
	normal reproductive system phenotype	J:300487

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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