Adgrg6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adgrg6
adhesion G protein-coupled receptor G6
MGI:1916151

60 phenotypes from 7 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adgrg6^em1Jlp/Adgrg6^em1Jlp C57BL/6-Adgrg6^em1Jlp	abnormal forelimb morphology	J:315981
	abnormal hindlimb morphology	J:315981
	abnormal locomotor behavior	J:315981
	abnormal motor coordination/balance	J:315981
	abnormal myelination	J:315981
	abnormal nervous system development	J:315981
	normal cardiovascular system phenotype	J:315981
	decreased body size	J:315981
	joint contracture	J:315981
	normal mortality/aging	J:315981
Adgrg6^em2Jlp/Adgrg6^em2Jlp C57BL/6-Adgrg6^em2Jlp	abnormal heart development	J:315981
	abnormal interventricular septum morphology	J:315981
	abnormal myocardial trabeculae morphology	J:315981
	abnormal placenta physiology	J:315981
	abnormal trophoblast glycogen cell morphology	J:315981
	abnormal trophoblast layer morphology	J:315981
	abnormal uterine spiral artery morphology	J:315981
	abnormal uterine spiral artery remodeling	J:315981
	dilated heart ventricle	J:315981
	disorganized placental labyrinth	J:315981
	embryonic lethality during organogenesis, complete penetrance	J:315981
	increased placenta intervillous maternal lacunae size	J:315981
	placenta hemorrhage	J:315981
	thin myocardium compact layer	J:315981
	thin ventricular wall	J:315981
Adgrg6^em2Jlp/Adgrg6^em3Jlp Mesp1^tm2(cre)Ysa/Mesp1⁺ involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	no abnormal phenotype detected	J:315981
Adgrg6^em2Jlp/Adgrg6^em3Jlp Tg(Tek-cre)1Ywa/0 involves: C57BL/6 * SJL	no abnormal phenotype detected	J:315981
Adgrg6^em3Jlp/Adgrg6^em3Jlp Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: C57BL/6 * CBA	decreased body size	J:315981
	embryonic lethality during organogenesis, complete penetrance	J:315981
	joint contracture	J:315981
	lethality throughout fetal growth and development, incomplete penetrance	J:315981
	small heart	J:315981
Adgrg6^em3Jlp/Adgrg6^em3Jlp Mesp1^tm2(cre)Ysa/Mesp1⁺ involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	no abnormal phenotype detected	J:315981
Adgrg6^em3Jlp/Adgrg6^em3Jlp Nfatc1^tm1.1(cre)Bz/Nfatc1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:315981
Adgrg6^em3Jlp/Adgrg6^em3Jlp Tg(Tek-cre)1Ywa/0 involves: C57BL/6 * SJL	no abnormal phenotype detected	J:315981
Adgrg6^tm1Apr/Adgrg6^tm1Apr either: 129S/SvEv-Gpr126^tm1Apr or B6.129S-Gpr126^tm1Apr or (involves: 129S/SvEv * MF1)	abnormal blood circulation	J:167309
	dilated heart ventricle	J:167309
	edema	J:167309
	embryonic lethality during organogenesis, complete penetrance	J:167309
	internal hemorrhage	J:167309
	thin myocardium	J:167309
Adgrg6^tm1Arte/Adgrg6^tm1Arte Tg(Col2a1-cre)#Amc/0 involves: 129S5/SvEvBrd	abnormal intervertebral disk morphology	J:224002, J:313834
	abnormal nucleus pulposus morphology	J:313834
	abnormal sternum morphology	J:224002
	increased chondrocyte apoptosis	J:224002
	scoliosis	J:224002, J:313834
	normal skeleton phenotype	J:224002, J:313834
Adgrg6^tm1Arte/Adgrg6^tm1Arte Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0 involves: 129S5/SvEvBrd	abnormal intervertebral disk morphology	J:313834
	scoliosis	J:313834
Adgrg6^tm1Arte/Adgrg6^tm1Arte Tg(Scx-GFP/cre)1Stzr/0 involves: 129S5/SvEvBrd	abnormal intervertebral disk morphology	J:313834
	abnormal nucleus pulposus morphology	J:313834
	abnormal tendon physiology	J:313834
	scoliosis	J:313834
Adgrg6^tm1Lex/Adgrg6^tm1Lex involves: 129S/SvEvBrd	myocardial trabeculae hypoplasia	J:202002
Adgrg6^tm1Lex/Adgrg6^tm1Lex involves: 129S/SvEvBrd * C57BL/6	abnormal axon fasciculation	J:173574
	abnormal axon morphology	J:173574
	abnormal axon radial sorting	J:173574
	abnormal cochlear nerve morphology	J:173574
	abnormal myelination	J:173574
	abnormal Schwann cell morphology	J:173574
	abnormal sciatic nerve morphology	J:173574
	abnormal somatic nervous system morphology	J:173574
	akinesia	J:173574
	decreased body size	J:173574
	impaired limb coordination	J:173574
	joint contracture	J:173574
	postnatal growth retardation	J:173574
	prenatal lethality, incomplete penetrance	J:173574
	preweaning lethality, complete penetrance	J:173574
Adgrg6^tm1Taki/Adgrg6^tm1Taki involves: C57BL/6	abnormal endocardium morphology	J:202002
	abnormal fetal cardiomyocyte mitochondrial morphology	J:202002
	abnormal fetal cardiomyocyte morphology	J:202002
	abnormal mitochondrial crista morphology	J:202002
	abnormal mitochondrial morphology	J:202002
	abnormal mitochondrial shape	J:202002
	abnormal myocardial trabeculae morphology	J:202002
	normal cardiovascular system phenotype	J:202002
	embryonic lethality during organogenesis, complete penetrance	J:202002
	increased cardiac muscle triglyceride level	J:202002
	pericardial edema	J:202002
	thin ventricular wall	J:202002

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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