Pygo2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pygo2
pygopus 2
MGI:1916161

50 phenotypes from 6 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pygo2^tm1.1Kba/Pygo2^tm1.1Kba involves: 129S6/SvEvTac * C57BL/6N * C57BL/6NTac	normal mortality/aging	J:198562
	normal reproductive system phenotype	J:198562
Pygo2^tm1.1Ssp/Pygo2^tm1.1Ssp Tg(CMV-cre)1Cgn/? involves: 129S1/Sv * 129X1/SvJ * BALB/cJ	abnormal kidney development	J:121416
	abnormal optic cup morphology	J:121416
	aphakia	J:121416
	decreased fetal size	J:121416
	microphthalmia	J:121416
	neonatal lethality, incomplete penetrance	J:121416
	small lens	J:121416
Pygo2^tm1.1Ssp/Pygo2^tm1.1Ssp Tg(Pax6-cre,GFP)1Pgr/? involves: 129S1/Sv * 129X1/SvJ * FVB	abnormal lens epithelium morphology	J:121416
	abnormal lens induction	J:121416
	abnormal optic placode morphology	J:121416
	aphakia	J:121416
	small lens	J:121416
	small optic pit	J:121416
Pygo2^tm1.1Ssp/Pygo2^tm1.2Ssp H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	small lens	J:121416
Pygo2^tm1.1Ssp/Pygo2^tm1.2Ssp H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tg(Pax6-cre,GFP)1Pgr/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * FVB	small lens	J:121416
Pygo2^tm1.1Ssp/Pygo2^tm1.2Ssp Tfap2a^tm1(cre)Moon/? involves: 129S1/Sv * 129X1/SvJ	abnormal lens induction	J:121416
	small lens	J:121416
Pygo2^tm1.1Ssp/Pygo2^tm1.2Ssp Tg(Pax6-cre,GFP)1Pgr/? involves: 129S1/Sv * 129X1/SvJ * FVB	small lens	J:121416
Pygo2^tm1.1Xdai/Pygo2^tm1.2Xdai Tg(KRT14-cre)#Smr/0 involves: 129P2/OlaHsd * C57BL/6J * SJL/J	abnormal branching of the mammary ductal tree	J:163218
	abnormal mammary gland development	J:163218
	abnormal mammary gland embryonic development	J:163218
	abnormal mammary gland growth during lactation	J:163218
	abnormal mammary gland growth during pregnancy	J:163218
	decreased mammary gland epithelial cell proliferation	J:163218
	lactation failure	J:163218
Pygo2^tm1.2Ssp/Pygo2^tm1.2Ssp Tg(CMV-cre)1Cgn/? involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss	abnormal kidney morphology	J:121918
	abnormal ureter development	J:121918
	aphakia	J:121918
	cleft palate	J:121918
	decreased fetal size	J:121918
	exencephaly	J:121918
	fetal growth retardation	J:121918
	neonatal lethality, complete penetrance	J:121918
Pygo2^tm1.2Xdai/Pygo2^tm1.2Xdai involves: 129P2/OlaHsd	decreased mammary gland epithelial cell proliferation	J:163218
Pygo2^tm1.2Xdai/Pygo2^tm1.2Xdai involves: 129P2/OlaHsd * C57BL/6	abnormal cornea morphology	J:121776
	abnormal hair follicle development	J:121776
	abnormal lens development	J:121776
	abnormal lens epithelium morphology	J:121776
	abnormal lens fiber morphology	J:121776
	abnormal lung development	J:121776
	abnormal retina morphology	J:121776
	abnormal small intestine morphology	J:121776
	aphakia	J:121776
	decreased birth body size	J:121776
	decreased birth weight	J:121776
	delayed eyelid opening	J:121776
	domed cranium	J:121776
	exencephaly	J:121776
	increased brain size	J:121776
	microphthalmia	J:121776
	perinatal lethality, complete penetrance	J:121776
	small lens	J:121776
Pygo2^{tm1b(EUCOMM)Wtsi}/Pygo2⁺ C57BL/6N-Pygo2^{tm1b(EUCOMM)Wtsi}/Tcp	abnormal kidney morphology	J:211773
	persistence of hyaloid vascular system	J:211773
Pygo2^{tm1b(EUCOMM)Wtsi}/Pygo2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Pygo2^{tm1b(EUCOMM)Wtsi}/Tcp	abnormal craniofacial morphology	J:211773
	abnormal eye morphology	J:211773
	abnormal hindbrain morphology	J:211773
	abnormal limb morphology	J:211773
	abnormal midbrain morphology	J:211773
	abnormal neural tube closure	J:211773
	anophthalmia	J:211773
	edema	J:211773
	hemorrhage	J:211773
	microphthalmia	J:211773
	preweaning lethality, complete penetrance	J:211773

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