Dnai1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnai1
dynein axonemal intermediate chain 1
MGI:1916172

33 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnai1^b2b284Clo/Dnai1^b2b284Clo C57BL/6J-Dnai1^b2b284Clo	abdominal situs ambiguus	J:175213
	abnormal aortic arch morphology	J:216862
	abnormal cardiovascular system morphology	J:216862
	abnormal motile cilium morphology	J:216862
	abnormal motile cilium physiology	J:216862
	abnormal respiratory motile cilium morphology	J:216862
	atrioventricular septal defect	J:175213
	bronchial situs inversus	J:175213
	dextrocardia	J:175213
	double outlet right ventricle	J:175213, J:216862
	heterotaxia	J:175213, J:216862
	hydrocephaly	J:216862
	postnatal lethality	J:216862
	situs inversus totalis	J:175213, J:216862
	ventricular septal defect	J:216862
Dnai1^b2b1526Clo/Dnai1^b2b1526Clo C57BL/6J-Dnai1^b2b1526Clo	abdominal situs ambiguus	J:175213
	abdominal situs inversus	J:175213
	aorta stenosis	J:175213
	dextrocardia	J:175213
	dual inferior vena cava	J:175213
	heterotaxia	J:175213
	immotile respiratory cilia	J:175213
	left pulmonary isomerism	J:175213
	micrognathia	J:175213
	short snout	J:175213
	situs inversus totalis	J:175213
	spleen hypoplasia	J:175213
Dnai1^em1Osb/Dnai1^em1Osb involves: C57BL/6NJcl * DBA/2NJcl	no abnormal phenotype detected	J:231237
Dnai1^tm1.1Leo/Dnai1^tm1.1Leo Not Specified	abnormal respiratory sounds	J:161297
	coughing	J:161297
	sneezing	J:161297
Dnai1^tm1.1Leo/Dnai1^tm1.1Leo Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺ involves: 129 * C57BL/6	abnormal mucociliary clearance	J:155730
	abnormal respiratory system physiology	J:155730
	normal nervous system phenotype	J:155730
	rhinosinusitis	J:155730
Dnai1^tm1.2Leo/Dnai1^tm1.2Leo involves: 129 * C57BL/6	astrocytosis	J:154976
	dilated brain ventricle	J:154976
	hydrocephaly	J:154976

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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