Pink1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pink1
PTEN induced putative kinase 1
MGI:1916193

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Park7^Gt(XE726)Byg/Park7^Gt(XE726)Byg Pink1^tm1.1Wrst/Pink1^tm1.1Wrst involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6J	normal cellular phenotype	J:242309
Park7^Gt(XE726)Byg/Park7^Gt(XE726)Byg Pink1^tm1.1Wrst/Pink1^tm1.1Wrst Rrn3^tm1.1Igt/Rrn3^tm1.1Igt Tg(Slc6a3-cre/ERT2)1Span/0 involves: 129 * 129P2/OlaHsd * 129S2/SvPas * C57BL/6J	abnormal cell physiology	J:242309
	abnormal nucleolus morphology	J:242309
Parl^tm1.1Bdes/Parl^tm1.1Bdes Pgam5^{tm1d(EUCOMM)Wtsi}/Pgam5^{tm1d(EUCOMM)Wtsi} Pink1^tm1.1Wrst/Pink1^tm1.1Wrst involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6N	neuron degeneration	J:269785
	premature death	J:269785
Parl^tm1.1Bdes/Parl^tm1.1Bdes Pink1^tm1.1Wrst/Pink1^tm1.1Wrst involves: 129P2/OlaHsd * 129S2/SvPas	neuron degeneration	J:269785
	premature death	J:269785
Pgam5^{tm1d(EUCOMM)Wtsi}/Pgam5^{tm1d(EUCOMM)Wtsi} Pink1^tm1.1Wrst/Pink1^tm1.1Wrst involves: 129S2/SvPas * C57BL/6N	normal mortality/aging	J:269785
Pink1^tm1.1Wrst/Pink1^tm1.1Wrst Tg(Prnp-SNCAA53T)AAub/? involves: 129S2/SvPas C57BL/6J * FVB/N	abnormal cell physiology	J:242309
	abnormal dopaminergic neuron morphology	J:242309
	abnormal nucleolus morphology	J:242309
	premature death	J:242309
Pink1^tm1Aub/Pink1^tm1Aub Tg(Prnp-SNCAA53T)AAub/Tg(Prnp-SNCAA53T)AAub involves: 129S/SvEv * FVB/N	abnormal locomotor behavior	J:214065
	abnormal motor neuron morphology	J:214065
	abnormal neurite morphology	J:214065
	alpha-synuclein inclusion body	J:214065
	decreased locomotor activity	J:214065
	decreased stereotypic behavior	J:214065
	decreased vertical activity	J:214065
	hindlimb paralysis	J:214065
	kyphosis	J:214065
	neurodegeneration	J:214065
	paresis	J:214065
	premature death	J:214065
Pink1^tm1Zhzh/Pink1^tm1Zhzh Slc6a3^tm4.1(tTA)Xz/? Tg(tetO-SNCAA53T)E2Cai/? involves: 129P2/OlaHsd 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6	abnormal mitochondrial morphology	J:218892
	neuronal cytoplasmic inclusions	J:218892

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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