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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Srrm4
serine/arginine repetitive matrix 4
MGI:1916205
44 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Srrm4bv/Srrm4bv
involves: 129 		abnormal cochlear inner hair cell morphology J:31165
cochlear inner hair cell degeneration J:31165
Srrm4bv/Srrm4bv
Not Specified 		abnormal cochlear hair cell development J:39922
abnormal cochlear inner hair cell morphology J:6106, J:13866
abnormal crista ampullaris morphology J:13866
abnormal distortion product otoacoustic emission J:117755
abnormal hearing electrophysiology J:32693
abnormal inner ear morphology J:13866, J:28889
abnormal otoacoustic response J:32693
abnormal pillar cell morphology J:6106
abnormal pinna reflex J:6106
abnormal utricular macula morphology J:28889
abnormal vestibular hair cell morphology J:28889
absent cochlear inner hair cells J:6106
absent pillar cells J:6106
absent vestibular hair cell stereocilia J:193641
circling J:39922
cochlear ganglion degeneration J:6106
cochlear inner hair cell degeneration J:39922
deafness J:6106, J:13866, J:193641
decreased cochlear inner hair cell number J:193641
decreased vestibular hair cell number J:193641
head tossing J:39922
impaired balance J:193641
increased or absent threshold for auditory brainstem response J:117755
utricular macular degeneration J:28889
Srrm4bv/Srrm4bv
Tg(Myo7a-Srrm4)#Bban/0
Not Specified 		normal behavior/neurological phenotype J:193641
normal hearing/vestibular/ear phenotype J:193641
Srrm4tm1b(EUCOMM)Wtsi/Srrm4+
involves: C57BL/6J * C57BL/6N 		abnormal axon guidance J:221584
abnormal stratification in cerebral cortex J:221584
Srrm4tm1b(EUCOMM)Wtsi/Srrm4tm1b(EUCOMM)Wtsi
involves: C57BL/6J * C57BL/6N 		abnormal axon extension J:221584
abnormal axon guidance J:221584
abnormal corpus callosum morphology J:221584
abnormal embryonic/fetal subventricular zone morphology J:221584
abnormal innervation J:221584
abnormal neurite morphology J:221584
abnormal phrenic nerve innervation pattern to diaphragm J:221584
abnormal stratification in cerebral cortex J:221584
circling J:221584
cyanosis J:221584
decreased neuron number J:221584
decreased neuronal precursor cell number J:221584
decreased survivor rate J:221584
head tilt J:221584
neonatal lethality, incomplete penetrance J:221584
premature neuronal precursor differentiation J:221584
respiratory distress J:221584
tremors J:221584
Srrm4tm1e(EUCOMM)Wtsi/Srrm4tm1e(EUCOMM)Wtsi
C57BL/6N-Srrm4tm1e(EUCOMM)Wtsi/Wtsi 		preweaning lethality, incomplete penetrance J:211773
tremors J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory