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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ctc1
CTS telomere maintenance complex component 1
MGI:1916214
18 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ctc1tm1.1Schg/Ctc1tm1.1Schg
involves: 129S7/SvEvBrd * C57BL/6 		abnormal bone marrow cell morphology/development J:184809
abnormal DNA repair J:184809
abnormal hematopoietic stem cell morphology J:184809
abnormal telomere length J:184809
chromosomal instability J:184809
decreased body size J:184809
decreased cell proliferation J:184809
decreased fibroblast proliferation J:184809
decreased hematopoietic stem cell number J:184809
decreased splenocyte proliferation J:184809
early cellular replicative senescence J:184809
impaired hematopoiesis J:184809
premature death J:184809
small spleen J:184809
small thymus J:184809
sparse hair J:184809
Ctc1tm1b(KOMP)Wtsi/Ctc1+
C57BL/6N-Ctc1tm1b(KOMP)Wtsi/Ieg 		decreased prepulse inhibition J:211773
Ctc1tm1b(KOMP)Wtsi/Ctc1tm1b(KOMP)Wtsi
C57BL/6N-Ctc1tm1b(KOMP)Wtsi/Ieg 		preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory