Rint1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rint1
RAD50 interactor 1
MGI:1916233

28 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rint1^{tm1b(KOMP)Wtsi}/Rint1⁺ C57BL/6N-Rint1^{tm1b(KOMP)Wtsi}/J	decreased circulating calcium level	J:211773
	decreased circulating free fatty acids level	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	increased circulating bilirubin level	J:211773
Rint1^{tm1b(KOMP)Wtsi}/Rint1^{tm1b(KOMP)Wtsi} C57BL/6N-Rint1^{tm1b(KOMP)Wtsi}/J	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Rint1^tm1Whl/Rint1⁺ Not Specified	increased cystadenoma incidence	J:122805
	increased hemangioma incidence	J:122805
	increased hepatocellular carcinoma incidence	J:122805
	increased keratoacanthoma incidence	J:122805
	increased lung adenocarcinoma incidence	J:122805
	increased lymphoma incidence	J:122805
	increased mammary adenocarcinoma incidence	J:122805
	increased mammary gland tumor incidence	J:122805
	increased mesothelioma incidence	J:122805
	increased ovary tumor incidence	J:122805
	increased papilloma incidence	J:122805
	increased pituitary adenoma incidence	J:122805
	increased skin squamous cell carcinoma incidence	J:122805
	increased tumor incidence	J:122805
	increased uterus leiomyoma incidence	J:122805
	premature death	J:122805
Rint1^tm1Whl/Rint1^tm1Whl Not Specified	abnormal embryo development	J:122805
	embryonic lethality between implantation and somite formation, complete penetrance	J:122805
	empty decidua capsularis	J:122805

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24