Prrt2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prrt2
proline-rich transmembrane protein 2
MGI:1916267

30 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prrt2^{tm1a(KOMP)Wtsi}/Prrt2⁺ C57BL/6N-A^tm1Brd Prrt2^{tm1a(KOMP)Wtsi}/Wtsi	jerky movement	J:237823
Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} C57BL/6N-A^tm1Brd Prrt2^{tm1a(KOMP)Wtsi}/Wtsi	abnormal excitatory synapse morphology	J:237823
	abnormal inhibitory postsynaptic currents	J:237823
	abnormal inhibitory synapse morphology	J:237823
	abnormal miniature excitatory postsynaptic currents	J:237823
	abnormal motor capabilities/coordination/movement	J:237823
	abnormal synaptic plasticity	J:237823
	audiogenic seizures	J:237823
	normal behavior/neurological phenotype	J:237823
	impaired balance	J:237823
	increased grooming behavior	J:237823
	increased susceptibility to pharmacologically induced seizures	J:237823
	induced hyperactivity	J:237823
	jerky movement	J:237823
	jumpy	J:237823
	normal nervous system phenotype	J:237823
	retropulsion	J:237823
	thin cerebral cortex	J:237823
Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} C57BL/6N-Prrt2^{tm1a(KOMP)Wtsi}/Wtsi	increased circulating amylase level	J:211773
Prrt2^{tm1b(KOMP)Wtsi}/Prrt2^{tm1b(KOMP)Wtsi} C57BL/6N-Prrt2^{tm1b(KOMP)Wtsi}/Ics	abnormal cued conditioning behavior	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased startle reflex	J:211773
	short tibia	J:211773
Prrt2^{tm1d(KOMP)Wtsi}/Prrt2⁺ B6(Cg)-Prrt2^{tm1d(KOMP)Wtsi}	decreased body weight	J:299667
	decreased excitatory postsynaptic current amplitude	J:299667
	dystonia	J:299667
	impaired coordination	J:299667
	impaired righting response	J:299667
Prrt2^{tm1d(KOMP)Wtsi}/Prrt2^{tm1d(KOMP)Wtsi} B6(Cg)-Prrt2^{tm1d(KOMP)Wtsi}	abnormal excitatory postsynaptic currents	J:299667
	abnormal synapse morphology	J:299667
	decreased body weight	J:299667
	decreased excitatory postsynaptic current amplitude	J:299667
	dystonia	J:299667
	impaired coordination	J:299667
	impaired righting response	J:299667
	increased locomotor activity	J:299667

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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