Gsdmd Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gsdmd
gasdermin D
MGI:1916396

6 phenotypes from 7 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gsdmd^em1Fcw/Gsdmd^em2Fcw involves: C57BL/6	abnormal macrophage apoptosis	J:226781
Gsdmd^em1Fcw/Gsdmd^em2Fcw involves: C57BL/6	decreased interleukin-1 beta secretion	J:226781
Gsdmd^em1Flv/Gsdmd^em1Flv C57BL/6N-Gsdmd^em1Flv	diarrhea	J:243487
Gsdmd^em1Flv/Gsdmd^em1Flv C57BL/6N-Gsdmd^em1Flv	increased susceptibility to Riboviria infection induced morbidity/mortality	J:243487
Gsdmd^em3Fcw/Gsdmd^em3Fcw involves: C57BL/6	abnormal macrophage apoptosis	J:226781
Gsdmd^em3Fcw/Gsdmd^em3Fcw involves: C57BL/6	decreased interleukin-1 beta secretion	J:226781
Gsdmd^em4Fcw/Gsdmd^em4Fcw C57BL/6N-Gsdmd^em4Fcw/J	abnormal macrophage apoptosis	J:101977
Gsdmd^em4Fcw/Gsdmd^em4Fcw C57BL/6N-Gsdmd^em4Fcw/J	abnormal susceptibility to bacterial infection	J:101977
Gsdmd^m1Btlr/Gsdmd^m1Btlr C57BL/6J-Gsdmd^m1Btlr	decreased interleukin-1 beta secretion	J:267555
Gsdmd^tm1.1Tshir/Gsdmd^tm1.1Tshir involves: C57BL/6 * CBA * ICR	no abnormal phenotype detected	J:140319

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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