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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fcmr
Fc fragment of IgM receptor
MGI:1916419
29 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fcmrtm1.2Khl/Fcmrtm1.2Khl
involves: C57BL/6 		abnormal granulocyte physiology J:194323
decreased B cell number J:174871
decreased circulating alanine transaminase level J:174871
decreased susceptibility to injury J:174871
decreased susceptibility to xenobiotic induced morbidity/mortality J:174871
normal immune system phenotype J:174871
increased T cell apoptosis J:174871
Fcmrtm1b(KOMP)Wtsi/Fcmrtm1b(KOMP)Wtsi
C57BL/6N-Fcmrtm1b(KOMP)Wtsi/Ucd 		decreased prepulse inhibition J:211773
enlarged adrenal glands J:211773
Fcmrtm1Mak/Fcmrtm1Mak
B6.129S2-Fcmrtm1Mak 		abnormal cytokine secretion J:194323
abnormal granulocyte physiology J:194323
decreased interleukin-6 secretion J:194323
decreased susceptibility to bacterial infection induced morbidity/mortality J:194323
decreased tumor necrosis factor secretion J:194323
normal hematopoietic system phenotype J:194323
impaired granulocyte bactericidal activity J:194323
increased susceptibility to bacterial infection J:194323
increased susceptibility to bacterial infection induced morbidity/mortality J:194323
Fcmrtm1Ohno/Fcmrtm1Ohno
B6.129-Fcmrtm1Ohno 		abnormal B cell morphology J:190117
abnormal immunoglobulin level J:190117
abnormal response to infection J:190117
decreased IgG1 level J:190117
decreased IgM level J:190117
decreased marginal zone B cell number J:190117
increased anti-chromatin antibody level J:190117
increased anti-double stranded DNA antibody level J:190117
increased B-1 B cell number J:190117
increased IgG3 level J:190117
increased IgM level J:190117
increased T cell number J:190117
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory