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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tmem127
transmembrane protein 127
MGI:1916720
30 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tmem127tm1(KOMP)Wtsi/Tmem127tm1(KOMP)Wtsi
C57BL/6N-Tmem127tm1(KOMP)Wtsi/Wtsi 		abnormal nail morphology J:211773
decreased B cell number J:211773
decreased B-2 B cell number J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased KLRG1-positive NK cell number J:211773
decreased KLRG1-positive T-helper cell number J:211773
decreased Ly6C high monocyte number J:211773
decreased memory-marker NK cell number J:211773
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
decreased NK cell number J:211773
decreased plasmacytoid dendritic cell number J:211773
increased alpha-beta T cell number J:211773
increased bone mineral content J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating amylase level J:211773
increased circulating bilirubin level J:211773
increased circulating creatinine level J:211773
increased KLRG1-positive NK cell number J:211773
increased Ly6C low monocyte number J:211773
increased memory-marker NK cell number J:211773
increased T cell number J:211773
thrombocytopenia J:211773
tremors J:211773
Tmem127tm1.1Pdah/Tmem127tm1.1Pdah
involves: BALB/cJ * C57BL/6 		abnormal cell morphology J:209071
abnormal lysosome physiology J:209071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory