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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pofut2
protein O-fucosyltransferase 2
MGI:1916863
20 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pofut2Gt(OST231463)Lex/Pofut2Gt(OST231463)Lex
involves: 129S5/SvEvBrd 		embryonic lethality, complete penetrance J:165751
Pofut2Gt(OST231463)Lex/Pofut2Gt(RST434)Byg
involves: 129P2/OlaHsd * 129S5/SvEvBrd 		embryonic lethality, complete penetrance J:165751
Pofut2Gt(RST434)Byg/Pofut2Gt(RST434)Byg
involves: 129P2/OlaHsd 		abnormal anterior visceral endoderm morphology J:165751
abnormal ectoderm development J:165751
abnormal embryo development J:165751
abnormal embryonic epiblast morphology J:165751
abnormal embryonic erythropoiesis J:165751
abnormal extraembryonic ectoderm morphology J:165751
abnormal physiological response to xenobiotic J:165751
abnormal Reichert's membrane morphology J:165751
abnormal vascular endothelial cell differentiation J:165751
absent primitive node J:165751
disorganized embryonic tissue J:165751
disorganized extraembryonic tissue J:165751
embryonic lethality between implantation and somite formation, complete penetrance J:165751
Pofut2tm2.2Bch/Pofut2tm2.2Bch
B6.Cg-Pofut2tm2.2Bch 		abnormal anterior visceral endoderm morphology J:234992
abnormal embryo morphology J:234992
abnormal extraembryonic tissue morphology J:234992
abnormal visceral endoderm morphology J:234992
absent mesoderm J:234992
disorganized embryonic tissue J:234992
disorganized extraembryonic tissue J:234992
embryonic lethality during organogenesis, complete penetrance J:234992
Pofut2tm2Bch/Pofut2tm2Bch
involves: C57BL/6 		embryonic lethality J:234992
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory