Arhgef12 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgef12
Rho guanine nucleotide exchange factor 12
MGI:1916882

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgef11^tm1Sgkd/Arhgef11⁺ Arhgef12^tm1Sgkd/Arhgef12^tm1Sgkd involves: 129 * C57BL/6J	preweaning lethality, complete penetrance	J:198274
Arhgef11^tm1Sgkd/Arhgef11^tm1Sgkd Arhgef12^tm1Sgkd/Arhgef12⁺ involves: 129 * C57BL/6J	preweaning lethality, incomplete penetrance	J:198274
Arhgef11^tm1Sgkd/Arhgef11^tm1Sgkd Arhgef12^tm1Sgkd/Arhgef12^tm1Sgkd involves: 129 * C57BL/6J	abnormal brain vasculature morphology	J:198274
	abnormal embryonic erythrocyte morphology	J:198274
	abnormal fibroblast proliferation	J:198274
	abnormal placental labyrinth vasculature morphology	J:198274
	abnormal vascular development	J:198274
	abnormal vitelline vasculature morphology	J:198274
	decreased embryo size	J:198274
	decreased fibroblast proliferation	J:198274
	disorganized yolk sac vascular plexus	J:198274
	normal embryo phenotype	J:198274
	embryonic lethality during organogenesis, complete penetrance	J:198274
	enlarged pericardium	J:198274
	thin placenta labyrinth	J:198274

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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