About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tnfaip8l2
tumor necrosis factor, alpha-induced protein 8-like 2
MGI:1917019
38 phenotypes from 1 allele in 1 genetic background
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Tnfaip8l2tm1Yhcn/Tnfaip8l2tm1Yhcn
129S6/SvEvTac-Tnfaip8l2tm1Yhcn 		abnormal B cell activation J:139785
abnormal B cell physiology J:139785
abnormal CD4-positive, alpha-beta T cell physiology J:139785
abnormal cytotoxic T cell physiology J:139785
abnormal inflammatory response J:139785
abnormal leukocyte morphology J:139785
abnormal macrophage activation involved in immune response J:139785
abnormal myeloid dendritic cell morphology J:139785
abnormal spleen morphology J:139785
abnormal T cell apoptosis J:139785
chronic inflammation J:139785
decreased IgG2a level J:139785
decreased IgG2b level J:139785
decreased survivor rate J:139785
enlarged spleen J:139785
increased B cell number J:139785
increased circulating interleukin-1 beta level J:139785
increased circulating interleukin-6 level J:139785
increased circulating interleukin-10 level J:139785
increased circulating interleukin-12 level J:139785
increased circulating tumor necrosis factor level J:139785
increased interferon-gamma secretion J:139785
increased interleukin-1 beta secretion J:139785
increased interleukin-2 secretion J:139785
increased interleukin-4 secretion J:139785
increased interleukin-6 secretion J:139785
increased interleukin-12 secretion J:139785
increased interleukin-17 secretion J:139785
increased spleen white pulp amount J:139785
increased susceptibility to endotoxin shock J:139785
increased T cell number J:139785
increased tumor necrosis factor secretion J:139785
intestinal inflammation J:139785
liver inflammation J:139785
lung inflammation J:139785
lymph node inflammation J:139785
spleen hyperplasia J:139785
weight loss J:139785
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory