About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rnf168
ring finger protein 168
MGI:1917488
53 phenotypes from 4 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Rnf168em1(IMPC)H/Rnf168em1(IMPC)H
C57BL/6NTac-Rnf168em1(IMPC)H/H 		abnormal coat/hair pigmentation J:211773
abnormal snout morphology J:211773
cornea opacity J:211773
increased circulating alanine transaminase level J:211773
increased circulating creatine kinase level J:211773
increased grip strength J:211773
narrow eye opening J:211773
Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal cell cycle checkpoint function J:198260
abnormal class switch recombination J:198260
abnormal Leydig cell morphology J:198260
abnormal male germ cell morphology J:198260
abnormal T cell receptor delta chain V(D)J recombination J:198260
chromosomal instability J:198260
decreased gamma-delta T cell number J:198260
decreased IgG1 level J:198260
decreased IgG2a level J:198260
decreased IgG3 level J:198260
decreased IgG level J:198260
decreased litter size J:198260
decreased male germ cell number J:198260
normal immune system phenotype J:198260
increased cellular sensitivity to ionizing radiation J:198260
increased cellular sensitivity to ultraviolet irradiation J:198260
increased DN3 thymocyte number J:198260
increased double-negative T cell number J:198260
normal neoplasm J:198260
reduced male fertility J:198260
small testis J:198260
testicular atrophy J:198260
Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal cell cycle checkpoint function J:198260
abnormal class switch recombination J:198260
abnormal Leydig cell morphology J:198260
abnormal male germ cell morphology J:198260
abnormal T cell receptor delta chain V(D)J recombination J:198260
chromosomal instability J:198260
decreased gamma-delta T cell number J:198260
decreased IgG1 level J:198260
decreased IgG2a level J:198260
decreased IgG3 level J:198260
decreased IgG level J:198260
decreased litter size J:198260
decreased male germ cell number J:198260
normal immune system phenotype J:198260
increased cellular sensitivity to ionizing radiation J:198260
increased cellular sensitivity to ultraviolet irradiation J:198260
increased DN3 thymocyte number J:198260
increased double-negative T cell number J:198260
normal neoplasm J:198260
reduced male fertility J:198260
small testis J:198260
testicular atrophy J:198260
Rnf168tm2b(EUCOMM)Hmgu/Rnf168tm2b(EUCOMM)Hmgu
C57BL/6N-Rnf168tm2b(EUCOMM)Hmgu/Ccpcz 		abnormal cornea morphology J:211773
abnormal cranium morphology J:211773
abnormal eye morphology J:211773
abnormal head morphology J:211773
abnormal heart morphology J:211773
abnormal skin morphology J:211773
abnormal spine curvature J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
anophthalmia J:211773
decreased body weight J:211773
decreased erythrocyte cell number J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
enlarged heart J:211773
enlarged thymus J:211773
fused cornea and lens J:211773
increased circulating alanine transaminase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating creatine kinase level J:211773
increased circulating lactate dehydrogenase level J:211773
increased circulating phosphate level J:211773
increased eosinophil cell number J:211773
increased grip strength J:211773
increased mean platelet volume J:211773
microphthalmia J:211773
vertebral fusion J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory