Bclaf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bclaf1
BCL2-associated transcription factor 1
MGI:1917580

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bclaf1^{tm1b(EUCOMM)Wtsi}/Bclaf1⁺ B6N(Cg)-Bclaf1^{tm1b(EUCOMM)Wtsi}/J	abnormal lens morphology	J:211773
	decreased grip strength	J:211773
	hyperactivity	J:211773
Bclaf1^{tm1b(EUCOMM)Wtsi}/Bclaf1^{tm1b(EUCOMM)Wtsi} B6N(Cg)-Bclaf1^{tm1b(EUCOMM)Wtsi}/J	cyanosis	J:211773
	preweaning lethality, complete penetrance	J:211773
Bclaf1^tm1Raz/Bclaf1⁺ involves: 129P2/OlaHsd * C57BL/6	decreased T cell proliferation	J:158087
Bclaf1^tm1Raz/Bclaf1^tm1Raz involves: 129P2/OlaHsd * C57BL/6	abnormal lung development	J:158087
	abnormal mesenchymal cell differentiation involved in lung development	J:158087
	absent gastric milk in neonates	J:158087
	decreased body size	J:158087
	decreased CD8-positive, alpha-beta T cell number	J:158087
	decreased T cell proliferation	J:158087
	increased B cell number	J:158087
	polydactyly	J:158087
	postnatal lethality, complete penetrance	J:158087
	thick lung-associated mesenchyme	J:158087
Tg(Myh6-Bclaf1)#Cya/0 Not Specified	decreased cardiac muscle contractility	J:301260
	increased cardiomyocyte apoptosis	J:301260
	increased circulating lactate dehydrogenase level	J:301260
	increased myocardial infarct size	J:301260

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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